Technology Process of 6-fluoro-8-methoxy-1-(2-methoxyphenyl)-3-methylimidazo[5,1-c][1,2,4]benzotriazine
There total 6 articles about 6-fluoro-8-methoxy-1-(2-methoxyphenyl)-3-methylimidazo[5,1-c][1,2,4]benzotriazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: nitric acid
2: potassium carbonate
3: potassium carbonate / N,N-dimethyl-formamide
4: tetrakis(triphenylphosphine) palladium(0)
5: iron; acetic acid
6: acetic acid; sodium nitrite
With
tetrakis(triphenylphosphine) palladium(0); nitric acid; iron; potassium carbonate; acetic acid; sodium nitrite;
In
N,N-dimethyl-formamide;
4: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.07.076
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate
2: potassium carbonate / N,N-dimethyl-formamide
3: tetrakis(triphenylphosphine) palladium(0)
4: iron; acetic acid
5: acetic acid; sodium nitrite
With
tetrakis(triphenylphosphine) palladium(0); iron; potassium carbonate; acetic acid; sodium nitrite;
In
N,N-dimethyl-formamide;
3: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.07.076
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide
2: tetrakis(triphenylphosphine) palladium(0)
3: iron; acetic acid
4: acetic acid; sodium nitrite
With
tetrakis(triphenylphosphine) palladium(0); iron; potassium carbonate; acetic acid; sodium nitrite;
In
N,N-dimethyl-formamide;
2: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.07.076