Phenyl(3-phenylaziridin-2-yl)methanone

Base Information

• Chemical Name: Phenyl(3-phenylaziridin-2-yl)methanone
• CAS No.: 51659-21-3
• Molecular Formula: C15H13 N O
• Molecular Weight: 223.274
• NSC Number: 167152,167104
• DSSTox Substance ID: DTXSID40304731
• Nikkaji Number: J1.095.413D
• Wikidata: Q71686842
• ChEMBL ID: CHEMBL1416701
• Mol file: 51659-21-3.mol

Synonyms:2-benzoyl-3-phenylaziridine;51659-21-3;phenyl(3-phenylaziridin-2-yl)methanone;phenyl-(3-phenylaziridin-2-yl)methanone;Phenyl-(3-phenyl-aziridin-2-yl)-methanone;NSC167152;MLS000767609;CHEMBL1416701;DTXSID40304731;HMS2798L03;NSC167104;STK379872;AKOS001086988;AKOS016881478;NSC-167104;NSC-167152;phenyl (3-phenylaziridin-2-yl)methanone;SMR000429949;EN300-11261;SR-01000059685;SR-01000059685-1;Z57040503

Chemical Property of Phenyl(3-phenylaziridin-2-yl)methanone

Chemical Property:

• Vapor Pressure: 6.98E-06mmHg at 25°C
• Boiling Point: 377°C at 760 mmHg
• Flash Point: 151.5°C
• Density: 1.172g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 223.099714038
• Heavy Atom Count: 17
• Complexity: 277

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2C(N2)C(=O)C3=CC=CC=C3

Technology Process of Phenyl(3-phenylaziridin-2-yl)methanone

There total 14 articles about Phenyl(3-phenylaziridin-2-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,3-diphenyl-3-methoxyaminopropan-1-one (52322-76-6) → phenyl (3-phenylaziridin-2-yl) methanone (51659-21-3)

Guidance literature:

With lanthanum(III) isopropoxide; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1016/S0040-4020(02)00983-3

Reference yield: 95.0%

1,3-diphenyl-propen-3-one (614-47-1) → trans-2-phenyl-3-benzoylaziridine (7570-84-5,51659-21-3,65309-87-7,74280-88-9)

Guidance literature:

With sodium hydride; N,N'-Diamino-1,4-diazoniabicyclo<2.2.2>octane Dinitrate; In isopropyl alcohol; benzene; at 0 ℃;

DOI:10.1039/b200046f

Reference yield: 95.0%

1,3-diphenyl-propen-3-one (614-47-1) → trans-2-phenyl-3-benzoylaziridine (7570-84-5,51659-21-3,65309-87-7,74280-88-9) + C15H13NO

Guidance literature:

With sodium hydroxide; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1055/s-2006-950425

upstream raw materials:

1,3-diphenyl-3-methoxyaminopropan-1-one

sodium methylate

1,3-diphenyl-propen-3-one

2,3-dibromo-1,3-diphenylpropane-1-one

Downstream raw materials:

N-((2R,3S)-2-Benzoyl-3-phenyl-aziridine-1-carbothioyl)-4-fluoro-benzamide

trans-1-phenylcarbamoyl-2-benzoyl-3-phenylaziridine

Phenyl-((4R,5S)-5-phenyl-2-phenylamino-4,5-dihydro-thiazol-4-yl)-methanone

(2R*,3R*) phenyl-3 (phenyl-1 vinyl)-2 aziridine