6-amino>-1-(4-fluorophenyl)-1-hexanone

Base Information

Chemical Name:6-amino>-1-(4-fluorophenyl)-1-hexanone
CAS No.:149775-00-8
Molecular Formula:C₂₂H₂₈FNO₂
Molecular Weight:357.468
Hs Code.:

6-<N-ethyl-N-<(2-methoxyphenyl)methyl>amino>-1-(4-fluorophenyl)-1-hexanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-amino>-1-(4-fluorophenyl)-1-hexanone

Chemical Property:

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Technology Process of 6-amino>-1-(4-fluorophenyl)-1-hexanone

There total 3 articles about 6-amino>-1-(4-fluorophenyl)-1-hexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026459-76-6
N-ethyl-N-[(2-methoxyphenyl)methyl]-N-[6-(4-fluorophenyl)-6-oxo-5-ethoxycarbonylhexyl]amine

: 149775-00-8
6-amino>-1-(4-fluorophenyl)-1-hexanone

Guidance literature:: With potassium hydroxide; In ethanol; for 6h; Heating;
DOI:10.1248/cpb.41.529

Reference yield:

: 1999-00-4
ethyl 3-(4'-fluorophenyl)-3-oxopropionate

: 149775-00-8
6-amino>-1-(4-fluorophenyl)-1-hexanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, 16 h

2: toluene / 12 h / Heating

3: aq. KOH / ethanol / 6 h / Heating

With potassium hydroxide; sodium hydride; In ethanol; toluene;
DOI:10.1248/cpb.41.529

Reference yield:

: 133899-51-1
6-Bromo-2-(4-fluoro-benzoyl)-hexanoic acid ethyl ester

: 149775-00-8
6-amino>-1-(4-fluorophenyl)-1-hexanone

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 12 h / Heating

2: aq. KOH / ethanol / 6 h / Heating

With potassium hydroxide; In ethanol; toluene;
DOI:10.1248/cpb.41.529