1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane

Base Information

• Chemical Name: 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane
• CAS No.: 503415-88-1
• Molecular Formula: C₂₀H₂₄N₂O₃
• Molecular Weight: 340.422
• Mol file: 503415-88-1.mol

Synonyms:

Chemical Property of 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane

There total 1 articles about 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-methyl-benzyl alcohol (89-95-2) + 7-amino-1,2-benzylidenedioxy-4-azaheptane → 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane (503415-88-1)

Guidance literature:

With acetic acid; In ethanol; for 24h; Heating;

DOI:10.1023/A:1020844216503

Reference yield: 79.0%

cobalt(II) chloride hexahydrate + 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane (503415-88-1) → [Co(OC6H4CHN(CH2)3NHCH2CHCH2O2CHC6H5)2]*5H2O

Guidance literature:

In ethanol; byproducts: HCl; heating of soln. of HOC6H4CHN(CH2)3NHCH2CHCH2O2CHC6H5 in anhyd. ethanol to the boiling point; addn. dropwise of soln. of CoCl2*6H2O in anhyd. ethanol for 30 min under continuous stirring; reflux for 24 h, stirring for 2 h at room temp.; pptn. filtration, washing with cold ethanol, diethyl ether and acetone, drying at room temp., elem. anal.;

DOI:10.1023/A:1020844216503

Reference yield: 75.0%

copper(II) choride dihydrate + 1,2-benzylidenedioxy-7-(2-hydroxybenzylideneamino)-4-azaheptane (503415-88-1) → [Cu(OC6H4CHN(CH2)3NHCH2CHCH2O2CHC6H5)(H2O)2](1+)*Cl(1-)=[Cu(OC6H4CHN(CH2)3NHCH2CHCH2O2CHC6H5)(H2O)2]Cl (503415-89-2)

Guidance literature:

In ethanol; byproducts: HCl; heating of soln. of HOC6H4CHN(CH2)3NHCH2CHCH2O2CHC6H5 in anhyd. ethanol to the boiling point; addn. dropwise of soln. of CuCl2*2H2O in anhyd. ethanol for 30 min under continuous stirring; reflux for 24 h, stirring for 2 h at room temp.; pptn. filtration, washing with cold ethanol, diethyl ether and acetone, drying at room temp., elem. anal.;

DOI:10.1023/A:1020844216503

upstream raw materials:

2-methyl-benzyl alcohol

Downstream raw materials:

[Cu(OC₆H₄CHN(CH₂)3NHCH₂CHCH₂O₂CHC₆H₅)(H₂O)2]⁽¹⁺⁾*Cl^(1-)=[Cu(OC₆H₄CHN(CH₂)3NHCH₂CHCH₂O₂CHC₆H₅)(H₂O)2]Cl