(8xi,9xi,14xi,17alpha)-3-oxoandrostan-17-yl alpha-L-idopyranosiduronic acid

Base Information

• Chemical Name: (8xi,9xi,14xi,17alpha)-3-oxoandrostan-17-yl alpha-L-idopyranosiduronic acid
• CAS No.: 31047-12-8
• Molecular Formula: C₂₅H₃₈O₈
• Molecular Weight: 466.572
• Mol file: 31047-12-8.mol

Synonyms:

Chemical Property of (8xi,9xi,14xi,17alpha)-3-oxoandrostan-17-yl alpha-L-idopyranosiduronic acid

Chemical Property:

• Vapor Pressure: 5.37E-20mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (8xi,9xi,14xi,17alpha)-3-oxoandrostan-17-yl alpha-L-idopyranosiduronic acid

There total 2 articles about (8xi,9xi,14xi,17alpha)-3-oxoandrostan-17-yl alpha-L-idopyranosiduronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-D-glucuronyl fluoride (777038-38-7) + Stanolone (521-18-6) → Dihydrotestosterone glucuronide (42037-24-1,31047-12-8)

Guidance literature:

With Escherichia coli β-glucuronidase E504G mutant; In aq. phosphate buffer; tert-butyl alcohol; at 37 ℃; for 48h; pH=7.5; Enzymatic reaction;

DOI:10.1039/c4ob00984c

Reference yield:

Stanolone (521-18-6) + D-Glucaro-1,4-lacton (389-36-6,13374-41-9,18404-60-9) → 5α-androstan-17β-ol-3-one-17-glucuronide (31047-12-8)

Guidance literature:

With recombinant human uridinne diphosphate-glucuronosyltransferase 1A₄ from HEK₂₉₃ cells; uridine 5'-diphosphoglucuronic acid triammonium salt; magnesium chloride; alamethicin; In dimethyl sulfoxide; at 37 ℃; pH=7.4; Reagent/catalyst; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1124/dmd.109.028712

upstream raw materials:

Stanolone

D-Glucaro-1,4-lacton

α-D-glucuronyl fluoride