3-Pentenoic acid, 5-[4-(4-chlorophenoxy)phenyl]-5-oxo-

Base Information

• Chemical Name: 3-Pentenoic acid, 5-[4-(4-chlorophenoxy)phenyl]-5-oxo-
• CAS No.: 105769-15-1
• Molecular Formula: C₁₇H₁₃ClO₄
• Molecular Weight: 316.741
• Mol file: 105769-15-1.mol

Synonyms:

Chemical Property of 3-Pentenoic acid, 5-[4-(4-chlorophenoxy)phenyl]-5-oxo-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pentenoic acid, 5-[4-(4-chlorophenoxy)phenyl]-5-oxo-

There total 6 articles about 3-Pentenoic acid, 5-[4-(4-chlorophenoxy)phenyl]-5-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-<4-(4-chlorophenoxy)benzoyl>butyric acid (57148-40-0) → 4-<4-(4-chlorophenoxy)benzoyl>-3-butenoic acid (105769-15-1)

Guidance literature:

Multi-step reaction with 6 steps

1: 74.2 percent / K₂CO₃ / dimethylformamide / 3 h / Ambient temperature

2: 64.1 percent / Br₂ / CHCl₃ / 3 h / Ambient temperature

3: 93.2 percent / ethanol; tetrahydrofuran / 0.5 h / Ambient temperature

4: 79.2 percent / m-chloroperbenzoic acid / 0.5 h / ice-cooling

5: 83.5 percent / NaOH / ethanol / 3 h / Ambient temperature

6: CCl₄ / 10 h / Heating

With sodium hydroxide; bromine; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; tetrachloromethane; ethanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1248/cpb.34.701

Reference yield:

ethyl 4-<4-(4-chlorophenoxy)benzoyl>butyrate (105769-07-1) → 4-<4-(4-chlorophenoxy)benzoyl>-3-butenoic acid (105769-15-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 64.1 percent / Br₂ / CHCl₃ / 3 h / Ambient temperature

2: 93.2 percent / ethanol; tetrahydrofuran / 0.5 h / Ambient temperature

3: 79.2 percent / m-chloroperbenzoic acid / 0.5 h / ice-cooling

4: 83.5 percent / NaOH / ethanol / 3 h / Ambient temperature

5: CCl₄ / 10 h / Heating

With sodium hydroxide; bromine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; tetrachloromethane; ethanol; chloroform;

DOI:10.1248/cpb.34.701

Reference yield:

ethyl 4-bromo-4-<4-(4-chlorophenoxy)benzoyl>butyrate (105769-09-3) → 4-<4-(4-chlorophenoxy)benzoyl>-3-butenoic acid (105769-15-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 93.2 percent / ethanol; tetrahydrofuran / 0.5 h / Ambient temperature

2: 79.2 percent / m-chloroperbenzoic acid / 0.5 h / ice-cooling

3: 83.5 percent / NaOH / ethanol / 3 h / Ambient temperature

4: CCl₄ / 10 h / Heating

With sodium hydroxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; tetrachloromethane; ethanol;

DOI:10.1248/cpb.34.701

upstream raw materials:

4-<4-(4-chlorophenoxy)benzoyl>-4-phenylsulfinylbutyric acid

4-<4-(4-chlorophenoxy)benzoyl>butyric acid

ethyl 4-<4-(4-chlorophenoxy)benzoyl>butyrate

ethyl 4-bromo-4-<4-(4-chlorophenoxy)benzoyl>butyrate

Refernces