1alpha,20-Dihydroxyvitamin D₃

Base Information

Chemical Name:1alpha,20-Dihydroxyvitamin D₃
CAS No.:158946-41-9
Molecular Formula:C₂₇H₄₄O₃
Molecular Weight:416.645
Hs Code.:

1alpha,20-Dihydroxyvitamin D<sub>3</sub>

Synonyms:

Suppliers and Price of 1alpha,20-Dihydroxyvitamin D₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1alpha,20-Dihydroxyvitamin D₃

Chemical Property:

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Technology Process of 1alpha,20-Dihydroxyvitamin D₃

There total 2 articles about 1alpha,20-Dihydroxyvitamin D₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 651734-12-2
20S-Hydroxyvitamin D₃

: 158946-41-9
1alpha,20-Dihydroxyvitamin D₃

Guidance literature:: 20S-Hydroxyvitamin D₃; With ethylenediaminetetraacetic acid; dioleoylphosphatidylcholine; sodium chloride; D,L-dithiothreitol; In aq. buffer; pH=7.4; Sonication;

With glucose-6-phosphate dehydrogenase; ethylenediaminetetraacetic acid; glucose-6-phosphate; mouse adrenodoxin; human adrenodoxin reductase; mouse CYP₂₇B₁; NADPH; sodium chloride; D,L-dithiothreitol; In aq. buffer; at 37 ℃; for 1h; pH=7.4;
DOI:10.1124/dmd.113.050955

Reference yield:

: 67-97-0
vitamin D₃

: 158946-41-9
1alpha,20-Dihydroxyvitamin D₃

Guidance literature:: Multi-step reaction with 2 steps

1.1: CYP11A1; heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin / Enzymatic reaction

2.1: dioleoylphosphatidylcholine; sodium chloride; D,L-dithiothreitol; ethylenediaminetetraacetic acid / aq. buffer / pH 7.4 / Sonication

2.2: 3407 / 1 h / 37 °C / pH 7.4

With ethylenediaminetetraacetic acid; CYP₁₁A₁; dioleoylphosphatidylcholine; sodium chloride; D,L-dithiothreitol; heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin; In aq. buffer;
DOI:10.1124/dmd.113.050955