Technology Process of benzyl (1-O-stearyl-2-O-palmityl-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosid)uronate
There total 2 articles about benzyl (1-O-stearyl-2-O-palmityl-sn-glyceryl 2,3,4-tri-O-benzyl-α-D-glucopyranosid)uronate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C55H74O10; 1-hexadecylcarboxylic acid;
With
1-[(1-(cyano-?2-?ethoxy-?2-?oxoethylidenaminooxy)?dimethylamino-?morpholino)]-uronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
for 0.166667h;
Inert atmosphere;
With
dmap;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 30h;
Inert atmosphere;
DOI:10.1021/jo302508e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine; 1-[(1-(cyano-?2-?ethoxy-?2-?oxoethylidenaminooxy)?dimethylamino-?morpholino)]-uronium hexafluorophosphate / N,N-dimethyl-formamide / 0.33 h / Inert atmosphere
1.2: 24 h / 50 °C / Inert atmosphere
2.1: ammonium cerium (IV) nitrate / water; acetonitrile / 2 h / 20 °C
3.1: N-ethyl-N,N-diisopropylamine; 1-[(1-(cyano-?2-?ethoxy-?2-?oxoethylidenaminooxy)?dimethylamino-?morpholino)]-uronium hexafluorophosphate / N,N-dimethyl-formamide / 0.17 h / Inert atmosphere
3.2: 30 h / 20 °C / Inert atmosphere
With
ammonium cerium (IV) nitrate; 1-[(1-(cyano-?2-?ethoxy-?2-?oxoethylidenaminooxy)?dimethylamino-?morpholino)]-uronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo302508e
