6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

Base Information

Chemical Name:6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester
CAS No.:141540-27-4
Molecular Formula:C₅₂H₆₁N₇O₁₅
Molecular Weight:1024.09
Hs Code.:

6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

Synonyms:

Suppliers and Price of 6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

There total 2 articles about 6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 157791-50-9
1-(5-carboxypentylamino)-4-nitro-9(10H)-acridinone

: 57816-11-2,62928-83-0,75283-21-5,76498-06-1,76498-09-4
N-<2-O-(benzyl 2-acetamido-2,3-dideoxy-β-D-glucopyranosid-3-yl)-D-lactoyl>-L-alanyl-D-isoglutamine benzyl ester

: 141540-27-4
6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In pyridine; N,N-dimethyl-formamide; at 4 - 20 ℃; for 72h;

Reference yield:

: (R)-4-{(S)-2-[(S)-2-((4aR,6R,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-hydroxy-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester

: 141540-27-4
6-(4-Nitro-9-oxo-9,10-dihydro-acridin-1-ylamino)-hexanoic acid (2R,3S,4R,5R,6R)-5-acetylamino-6-benzyloxy-4-{(S)-1-[(S)-1-((R)-3-benzyloxycarbonyl-1-carbamoyl-propylcarbamoyl)-ethylcarbamoyl]-ethoxy}-3-hydroxy-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 75percent aq. AcOH

2: dicyclohexylcarbodiimide (DCC), 1-hydroxybenzotriazole (HOBt) / pyridine; dimethylformamide / 72 h / 4 - 20 °C

With benzotriazol-1-ol; acetic acid; dicyclohexyl-carbodiimide; In pyridine; N,N-dimethyl-formamide;