N-benzoyl-L-thiovaline amide

Base Information

• Chemical Name: N-benzoyl-L-thiovaline amide
• CAS No.: 93883-65-9
• Molecular Formula: C₁₂H₁₆N₂OS
• Molecular Weight: 236.338
• Mol file: 93883-65-9.mol

Synonyms:

Chemical Property of N-benzoyl-L-thiovaline amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzoyl-L-thiovaline amide

There total 14 articles about N-benzoyl-L-thiovaline amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → N-benzoyl-L-thiovaline amide (93883-65-9)

Guidance literature:

Multi-step reaction with 5 steps

3: NH₃ / methanol / 110 °C

4: POCl₃, Py

5: H₂S

With pyridine; hydrogen sulfide; ammonia; trichlorophosphate; In methanol;

DOI:10.1039/jr9610003394

Reference yield:

N-benzoyl-L-valine methyl ester (1492-13-3,14599-03-2,92077-72-0,10512-91-1) → N-benzoyl-L-thiovaline amide (93883-65-9)

Guidance literature:

Multi-step reaction with 3 steps

1: NH₃ / methanol / 110 °C

2: POCl₃, Py

3: H₂S

With pyridine; hydrogen sulfide; ammonia; trichlorophosphate; In methanol;

DOI:10.1039/jr9610003394

Reference yield:

(2R)-2-(benzoylamino)-3-methylbutyric acid methyl ester (1492-13-3) → N-benzoyl-D-thiovaline amide (93883-65-9)

Guidance literature:

Multi-step reaction with 3 steps

1: NH₃ / methanol / 110 °C

2: POCl₃, Py

3: H₂S

With pyridine; hydrogen sulfide; ammonia; trichlorophosphate; In methanol;

DOI:10.1039/jr9610003394

upstream raw materials:

(+/-)-α-Benzamino-isovaleriansaeure-nitril

benzoyl chloride

2-amino-3,3-dimethylpropionitrile hydrochloride

D-α-Benzamido-β-methylbutyronitril

Downstream raw materials:

2-(1-benzoylamino-2-methyl-propyl)-thiazole-4-carboxylic acid ethyl ester

2-((S)-1-benzoylamino-2-methyl-propyl)-thiazole-4-carboxylic acid ethyl ester

N-[(R)-2-methyl-1-(4-phenyl-thiazol-2-yl)-propyl]-benzamide

2-(1-benzoylamino-2-methyl-propyl)-thiazole-4-carboxylic acid