Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester
• CAS No.: 127156-25-6
• Molecular Formula: C₃₅H₄₆O₇S
• Molecular Weight: 610.812

Synonyms:

Chemical Property of Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester

There total 5 articles about Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-(S)-6-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-2-methyl-5-triethylsilanyloxy-hepta-3,6-dien-2-ol (127135-71-1) → Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester (127156-25-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) t-BuOOH; 2.) n-Bu₄NF / 1.) VO(acac)2 / 1.) benzene

2: DEAD/Ph₃P / benzene

With tert.-butylhydroperoxide; tetrabutyl ammonium fluoride; triphenylphosphine; diethylazodicarboxylate; bis(acetylacetonate)oxovanadium; In benzene;

DOI:10.1016/S0040-4039(01)80758-9

Reference yield:

2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-propenal (127156-24-5) → Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester (127156-25-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 78 percent

2: Bu₄NF

3: NEt₃, DMAP / CH₂Cl₂

4: 1.) t-BuOOH; 2.) n-Bu₄NF / 1.) VO(acac)2 / 1.) benzene

5: DEAD/Ph₃P / benzene

With tert.-butylhydroperoxide; dmap; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; diethylazodicarboxylate; bis(acetylacetonate)oxovanadium; In dichloromethane; benzene;

DOI:10.1016/S0040-4039(01)80758-9

Reference yield:

(E)-(S)-6-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-2-methyl-hepta-3,6-diene-2,5-diol (127135-76-6) → Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester (127156-25-6)

Guidance literature:

Multi-step reaction with 3 steps

1: NEt₃, DMAP / CH₂Cl₂

2: 1.) t-BuOOH; 2.) n-Bu₄NF / 1.) VO(acac)2 / 1.) benzene

3: DEAD/Ph₃P / benzene

With tert.-butylhydroperoxide; dmap; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; diethylazodicarboxylate; bis(acetylacetonate)oxovanadium; In dichloromethane; benzene;

DOI:10.1016/S0040-4039(01)80758-9

upstream raw materials:

2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-propenal

(E)-(S)-6-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-2-methyl-hepta-3,6-diene-2,5-diol

(E)-(S)-6-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-2-methyl-5-triethylsilanyloxy-hepta-3,6-dien-2-ol

(E)-(S)-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-6-methyl-6-triethylsilanyloxy-hepta-1,4-dien-3-ol

Downstream raw materials:

(2R,2'R,3'R)-3'-{1-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-Methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-vinyl}-3,3-dimethyl-[2,2']bioxiranyl

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 127156-25-6 Toluene-4-sulfonic acid (R)-1-[(2S,3S)-3-(1-hydroxy-1-methyl-ethyl)-oxiranyl]-2-[(1R,3R,3aR,3bS,6R,6aR,6bR)-3-(4-methoxy-benzyloxy)-3a,6-dimethyl-decahydro-cyclobutadicyclopenten-1-yl]-allyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send