(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Base Information

Chemical Name:(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester
CAS No.:73341-24-9
Molecular Formula:C₄₃H₅₃N₅O₁₄
Molecular Weight:863.919
Hs Code.:

(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Synonyms:

Suppliers and Price of (R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

There total 2 articles about (R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.4%

: 1738-86-9
Z-Gly-ONp

: 57816-11-2,62928-83-0,75283-21-5,76498-06-1,76498-09-4
benzyl 2-acetamido-2-deoxy-3-O-(D-2-propanoyl-L-alanyl-D-isoglutamine benzyl ester)-α-D-glucopyranoside

: 73341-24-9
(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Guidance literature:: With N-ethylmorpholine;; benzotriazol-1-ol; In N,N-dimethyl-formamide; for 16h; Ambient temperature;
DOI:10.1248/cpb.29.2215

Reference yield:

: 71811-18-2
N-acetyl-1-O-benzyl-4,6-O-benzylidene-α-muramyl-α-aminoisobutyryl-D-isoglutamine benzyl ester

: 73341-24-9
(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / acetic acid (75percent) / 0.5 h / Heating

2: 65.4 percent / 1-hydroxybenzotriazole, N-ethylmorpholine / dimethylformamide / 16 h / Ambient temperature

With N-ethylmorpholine;; benzotriazol-1-ol; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.29.2215

Reference yield:

: 73341-24-9
(R)-4-((S)-2-{2-[(2S,3R,4R,5S,6R)-3-Acetylamino-2-benzyloxy-6-(2-benzyloxycarbonylamino-acetoxymethyl)-5-hydroxy-tetrahydro-pyran-4-yloxy]-propionylamino}-propionylamino)-4-carbamoyl-butyric acid benzyl ester

: (R)-4-{(S)-2-[2-((2S,3R,4R,5S,6R)-3-Acetylamino-6-{2-[3-(4,5-dimethoxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl)-propionylamino]-acetoxymethyl}-2,5-dihydroxy-tetrahydro-pyran-4-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 84.4 percent / hydrogen / palladium black / acetic acid / 3 h / Ambient temperature

2: 67.1 percent / ethylmorpholine / dimethylformamide / 16 h / Ambient temperature

With 2-ethylmorpholine; hydrogen; palladium; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.29.2215