Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate

Base Information

Chemical Name:Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate
CAS No.:72948-93-7
Molecular Formula:C₁₇H₂₃NO₃
Molecular Weight:289.375
Hs Code.:
DSSTox Substance ID:DTXSID101139778

Synonyms:72948-93-7;Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate;DTXSID101139778;Carbamic acid, [(4-hydroxybicyclo[2.2.2]oct-1-yl)methyl]-, phenylmethyl ester

Suppliers and Price of Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:289.16779360
Heavy Atom Count:21
Complexity:352

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2(CCC1(CC2)CNC(=O)OCC3=CC=CC=C3)O

Technology Process of Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate

There total 6 articles about Benzyl N-[(4-hydroxy-1-bicyclo[2.2.2]octanyl)methyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72948-77-7
ethyl 4-hydroxyspiro[bicyclo[2.2.2]octane-2,2'-[1,3]dithiolane]-1-carboxylate

: 72948-93-7
4-N-Benzyloxycarbonylaminomethyl-bicyclo<2.2.2>octan-1-ol

Guidance literature:: Multi-step reaction with 6 steps

1: Raney-Ni / ethanol / Heating

2: N₂H₄*H₂O / ethanol / Heating

3: Raney-Ni / ethanol / Heating

4: 4-nitro-benzenesulfonyl chloride, Py

5: (i) LiAlH₄, (ii) aq. NaOH

6: Et₃N

With pyridine; hydrazine hydrate; triethylamine; 4-Nitrobenzenesulfonyl chloride; nickel; In ethanol;
DOI:10.1002/hlca.19790620830

Reference yield:

: 72948-79-9
4-Hydroxy-bicyclo<2.2.2>octan-1-carbonsaeurehydrazid

: 72948-93-7
4-N-Benzyloxycarbonylaminomethyl-bicyclo<2.2.2>octan-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1: Raney-Ni / ethanol / Heating

2: 4-nitro-benzenesulfonyl chloride, Py

3: (i) LiAlH₄, (ii) aq. NaOH

4: Et₃N

With pyridine; triethylamine; 4-Nitrobenzenesulfonyl chloride; nickel; In ethanol;
DOI:10.1002/hlca.19790620830

Reference yield:

: 72948-78-8
ethyl 4-hydroxybicyclo[2.2.2]octane-1-carboxylate

: 72948-93-7
4-N-Benzyloxycarbonylaminomethyl-bicyclo<2.2.2>octan-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: N₂H₄*H₂O / ethanol / Heating

2: Raney-Ni / ethanol / Heating

3: 4-nitro-benzenesulfonyl chloride, Py

4: (i) LiAlH₄, (ii) aq. NaOH

5: Et₃N

With pyridine; hydrazine hydrate; triethylamine; 4-Nitrobenzenesulfonyl chloride; nickel; In ethanol;
DOI:10.1002/hlca.19790620830