Chemical Property of Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-alpha-L-mannopyranosyl)-2-methoxy-24-methyl-
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Boiling Point:873.8°C at 760 mmHg
- Flash Point:251.5°C
- PSA：182.83000
- Density:1.18g/cm3
- LogP:4.19860
- XLogP3:5.5
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:13
- Rotatable Bond Count:10
- Exact Mass:782.48164228
- Heavy Atom Count:55
- Complexity:1360
- Purity/Quality:
-
>95% by HPLC *data from raw suppliers
Leucanicidin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC3C(C(C(C(O3)C)O)O)OC)O)O)OC)C
- Isomeric SMILES:CC1C/C(=C/C=C\C(C(OC(=O)/C(=C\C(=C\C(C1O)C)\C)/OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)OC3C(C(C(C(O3)C)O)O)OC)O)O)OC)/C
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Uses
Leucanicidin is a potent nematocide and insecticide belonging to the bafilomycin class. Lack of access to the pure metabolite has limited its investigation, however structural differences between leucanicidin and the bafilomycins offer scope for investigations into the use of V-ATPases as therapeutic targets. Leucanicidin is a potent nematocide and insecticide of the bafilomycin class.
