5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid

Base Information

Chemical Name:5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid
CAS No.:115891-15-1
Molecular Formula:C₁₂H₉BrN₂O₂
Molecular Weight:293.12
Hs Code.:
DSSTox Substance ID:DTXSID601233129

Synonyms:5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid;DTXSID601233129;AKOS011267880;115891-15-1

Suppliers and Price of 5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:291.98474
Heavy Atom Count:17
Complexity:269

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=C(C=C(C=N2)Br)C(=O)O

Technology Process of 5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid

There total 1 articles about 5-Bromo-2-(phenylamino)-3-pyridinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 29241-65-4
5-bromo-2-chloronicotinic acid

: 62-53-3
aniline

: 115891-15-1
5-Bromo-2-phenylamino-nicotinic acid

Guidance literature:: DOI:10.1021/jm00119a010

Reference yield:

: 115891-15-1
5-Bromo-2-phenylamino-nicotinic acid

: 115891-38-8
methyl 5-bromo-2-phenylaminopyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetone / 1.) 0 deg C, 2.) heating, 18 h

2: 85 percent / triethylamine / methanol / 6 h / Heating

With triethylamine; In methanol; acetone;
DOI:10.1021/jm00119a010

Reference yield:

: 115891-15-1
5-Bromo-2-phenylamino-nicotinic acid

: 115891-73-1
6-Bromo-3-butyl-4-hydroxy-1-phenyl-1H-[1,8]naphthyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / acetone / 1.) 0 deg C, 2.) heating, 18 h

2: 85 percent / triethylamine / methanol / 6 h / Heating

3: 81 percent / potassium tert-butoxide / 1.) 0.25 h, 2.) heating, 4 h

With potassium tert-butylate; triethylamine; In methanol; acetone;
DOI:10.1021/jm00119a010