Technology Process of 6-(phenylamino)naphthalen-2-ylphosphonic dichloride
There total 5 articles about 6-(phenylamino)naphthalen-2-ylphosphonic dichloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene / 5 h / 190 °C / Inert atmosphere
1.2: Reflux; Inert atmosphere
2.1: nickel dichloride / 5 h / 180 °C / Inert atmosphere; Sealed tube
3.1: trimethylsilyl bromide / dichloromethane / 36 h / 20 °C / Inert atmosphere
3.2: 0.5 h / 20 °C
4.1: phosphorus pentachloride / 17 h / 90 °C / Inert atmosphere
With
trimethylsilyl bromide; phosphorus pentachloride; toluene-4-sulfonic acid; nickel dichloride;
In
5,5-dimethyl-1,3-cyclohexadiene; dichloromethane;
DOI:10.1002/anie.201100738
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: trimethylsilyl bromide / dichloromethane / 36 h / 20 °C / Inert atmosphere
1.2: 0.5 h / 20 °C
2.1: phosphorus pentachloride / 17 h / 90 °C / Inert atmosphere
With
trimethylsilyl bromide; phosphorus pentachloride;
In
dichloromethane;
DOI:10.1002/anie.201100738
- Guidance literature:
-
With
phosphorus pentachloride;
at 90 ℃;
for 17h;
Inert atmosphere;
DOI:10.1002/anie.201100738
