AURORA 636

Base Information

• Chemical Name: AURORA 636
• CAS No.: 303790-74-1
• Molecular Formula: C₁₉H₂₁NO₂
• Molecular Weight: 295.381
• Mol file: 303790-74-1.mol

Synonyms:

Chemical Property of AURORA 636

Chemical Property:

• Boiling Point: 379.2±35.0 °C(Predicted)
• PKA: 13.40±0.70(Predicted)
• Density: 1.108±0.06 g/cm3(Predicted)

Purity/Quality:

98%min ^*data from raw suppliers

N-(3-Acetylphenyl)-4-tert-butylbenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of AURORA 636

There total 2 articles about AURORA 636 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(3-aminophenyl)ethanone (99-03-6) + p-tert-butyl benzoyl chloride (1710-98-1) → N-(3-acetylphenyl)-4-(1,1-dimethylethyl)-benzamide (303790-74-1)

Guidance literature:

With sodium hydroxide;

DOI:10.3109/14756366.2011.587416

Reference yield:

→ N-(3-acetylphenyl)-4-(1,1-dimethylethyl)-benzamide (303790-74-1)

Guidance literature:

Reference yield: 100.0%

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + N-(3-acetylphenyl)-4-(1,1-dimethylethyl)-benzamide (303790-74-1) → C29H27NO2

Guidance literature:

N-(3-acetylphenyl)-4-(1,1-dimethylethyl)-benzamide; With sodium hydroxide; In ethanol; water; for 0.166667h;

Indole-3-carboxaldehyde; In ethanol; water; at 25 ℃; for 24h;

DOI:10.3109/14756366.2012.743536

upstream raw materials:

1-(3-aminophenyl)ethanone

p-tert-butyl benzoyl chloride

Refernces

• 1、 Bandgar, Babasaheb P.,Jalde, Shivkumar S.,Korbad, Balaji L.,Patil, Sachin A.,Chavan, Hemant V.,Kinkar, Santosh N.,Adsul, Laxman K.,Shringare, Sadanand N.,Nile, Shivraj H.. "Synthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics". scheme or table. p. 267 - 274. Retrieved 2012/07/13.
• 2、 Bandgar, Babasaheb P.,Hote, Baliram S.,Jalde, Shivkumar S.,Gacche, Rajesh N.. "Synthesis and biological evaluation of novel curcumin analogues as anti-inflammatory, anti-cancer and anti-oxidant agents". . p. 3006 - 3014. Retrieved 2012/10/29.