Technology Process of C27H24ClN3O4
There total 9 articles about C27H24ClN3O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride; potassium hydroxide;
In
methanol;
DOI:10.1021/jm401877m
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: acetyl chloride
2.1: triethylamine / dichloromethane
3.1: lithium aluminium tetrahydride / tetrahydrofuran
4.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 4 h / 0 °C
5.1: hydrogenchloride / ethyl acetate / 20 °C
6.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine / dichloromethane / 0.5 h
6.2: 4 h
7.1: hydroxylamine hydrochloride; potassium hydroxide / methanol
With
hydrogenchloride; lithium aluminium tetrahydride; hydroxylamine hydrochloride; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; acetyl chloride; triphenylphosphine; potassium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
4.1: |Mitsunobu Displacement;
DOI:10.1021/jm401877m
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine / dichloromethane / 0.5 h
1.2: 4 h
2.1: hydroxylamine hydrochloride; potassium hydroxide / methanol
With
hydroxylamine hydrochloride; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; potassium hydroxide;
In
methanol; dichloromethane;
DOI:10.1021/jm401877m
