N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide

Base Information

Chemical Name:N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide
CAS No.:86944-46-9
Molecular Formula:C₈H₆Br₃N₃O₃
Molecular Weight:431.866
Hs Code.:

Synonyms:Acetamide, N-[5-bromo-6-(dibromoacetyl)-1,4-dihydro-4-oxo-2-pyrimidinyl]-(9CI)

Suppliers and Price of N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:2.45g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide

There total 5 articles about N-[5-bromo-6-(dibromoacetyl)-4-oxo-1,4-dihydropyrimidin-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 86944-45-8
2-acetamido-6-(1-ethoxy-2-bromoethenyl)-4(1H)-pyrimidinone

: 86944-46-9
2-acetamido-5-bromo-6-(dibromoacetyl)-4(1H)-pyrimidinone

Guidance literature:: With N-Bromosuccinimide; In water; acetone;
DOI:10.1021/jo00169a001

Reference yield:

: 6312-89-6
ethyl 3-oxo-4,4-diethoxypentanoate

: 86944-46-9
2-acetamido-5-bromo-6-(dibromoacetyl)-4(1H)-pyrimidinone

Guidance literature:: Multi-step reaction with 5 steps

1: 42 percent / ethanol / 17 h / Heating

2: 67 percent / 0.17 h / 100 °C

3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating

4: 1) NBS, 2) p-TsOH / 1) EtOH, 35 deg C, 2) Xylene, reflux

5: 59 percent / NBS / H₂O; acetone

With N-Bromosuccinimide; o-toluenesulfonic acid; toluene-4-sulfonic acid; In ethanol; water; acetone; xylene;
DOI:10.1021/jo00169a001

Reference yield:

: 86944-23-2
2-amino-6-(1,1-diethoxyethyl)-4(1H)-pyrimidinone

: 86944-46-9
2-acetamido-5-bromo-6-(dibromoacetyl)-4(1H)-pyrimidinone

Guidance literature:: Multi-step reaction with 4 steps

1: 67 percent / 0.17 h / 100 °C

2: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating

3: 1) NBS, 2) p-TsOH / 1) EtOH, 35 deg C, 2) Xylene, reflux

4: 59 percent / NBS / H₂O; acetone

With N-Bromosuccinimide; o-toluenesulfonic acid; toluene-4-sulfonic acid; In water; acetone; xylene;
DOI:10.1021/jo00169a001