Technology Process of C19H24F3N3
There total 10 articles about C19H24F3N3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-ethyl-N,N-diisopropylamine / ethanol / 0.17 h / 140 °C / 4500.45 Torr / Microwave irradiation
2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); triphenylphosphine / N,N-dimethyl-formamide / 90 °C
4: hydrogen; palladium 10% on activated carbon / methanol / 20 °C / 760.05 Torr
5: hydrogenchloride / 1,4-dioxane; dichloromethane / 0 - 20 °C
With
hydrogenchloride; tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
1,4-dioxane; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
1: |Pictet-Spengler Synthesis / 3: |Stille Cross Coupling;
DOI:10.1016/j.bmcl.2013.01.088
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); triphenylphosphine / N,N-dimethyl-formamide / 90 °C
3: hydrogen; palladium 10% on activated carbon / methanol / 20 °C / 760.05 Torr
4: hydrogenchloride / 1,4-dioxane; dichloromethane / 0 - 20 °C
With
hydrogenchloride; tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;
2: |Stille Cross Coupling;
DOI:10.1016/j.bmcl.2013.01.088
