(1S,3S,5R,6R,8S₁₀S,11R)-phyllaemblic acid

Base Information

• Chemical Name: (1S,3S,5R,6R,8S₁₀S,11R)-phyllaemblic acid
• CAS No.: 270902-82-4
• Molecular Formula: C₂₁H₂₄O₉
• Molecular Weight: 420.416
• Mol file: 270902-82-4.mol

Synonyms:

Chemical Property of (1S,3S,5R,6R,8S₁₀S,11R)-phyllaemblic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,3S,5R,6R,8S₁₀S,11R)-phyllaemblic acid

There total 1 articles about (1S,3S,5R,6R,8S₁₀S,11R)-phyllaemblic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phyllaemblicin B → (1S,3S,5R,6R,8S10S,11R)-phyllaemblic acid (270902-82-4)

Guidance literature:

With sulfuric acid;

DOI:10.1021/np000135i

Reference yield:

(1S,3S,5R,6R,8S10S,11R)-phyllaemblic acid (270902-82-4) → (2S,4S,5R)-4-Benzoyloxy-2-methoxy-5-methyl-tetrahydro-pyran-2-carboxylic acid (270597-12-1)

Guidance literature:

With potassium permanganate; sodium periodate; In methanol; water; at 20 ℃; for 5h;

DOI:10.1016/S0040-4039(00)00015-0

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (1S,3S,5R,6R,8S10S,11R)-phyllaemblic acid (270902-82-4) → methyl ester of phyllaemblic acid (270597-09-6)

Guidance literature:

In methanol; diethyl ether; at 20 ℃;

DOI:10.1016/S0040-4039(00)00015-0

Downstream raw materials:

methyl ester of phyllaemblic acid

(2S,4S,5R)-4-Benzoyloxy-2-methoxy-5-methyl-tetrahydro-pyran-2-carboxylic acid