1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

Base Information

Chemical Name:1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester
CAS No.:112795-94-5
Molecular Formula:C₂₆H₃₁N₅O₆
Molecular Weight:509.562
Hs Code.:

1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

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Chemical Property of 1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

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Technology Process of 1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

There total 4 articles about 1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 112795-94-5
1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

Guidance literature:

Reference yield:

: 1-[2-(Benzyl-methyl-amino)-ethylcarbamoyl]-2-methoxy-4-methyl-6-(3-nitro-phenyl)-1,6-dihydro-pyrimidine-5-carboxylic acid isopropyl ester

: 112795-94-5
1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; methanol; Yield given;
DOI:10.1021/jm00106a048

Reference yield:

: 14165-18-5
N-benzyl-N-methylethylenediamine

: 112795-94-5
1,2,3,4-tetrahydro-6-methyl-3-[[[2-[methyl(phenylmethyl)amino]ethyl]amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) pyridine

2: aq. HCl / methanol; tetrahydrofuran

With pyridine; hydrogenchloride; In tetrahydrofuran; methanol;
DOI:10.1021/jm00106a048