(6S,7R,8S)-(-)-7-epi-goniodiol

Base Information

Chemical Name:(6S,7R,8S)-(-)-7-epi-goniodiol
CAS No.:1152589-20-2
Molecular Formula:C₁₃H₁₄O₄
Molecular Weight:234.252
Hs Code.:

Synonyms:

Suppliers and Price of (6S,7R,8S)-(-)-7-epi-goniodiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (6S,7R,8S)-(-)-7-epi-goniodiol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (6S,7R,8S)-(-)-7-epi-goniodiol

There total 6 articles about (6S,7R,8S)-(-)-7-epi-goniodiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 916151-83-2
(S)-6-((2S,3S)-3-phenyloxiran-2-yl)-5,6-dihydro-2H-pyran-2-one

: 1152589-20-2
(6S,7R,8S)-(-)-7-epi-goniodiol

: 474097-60-4
(6S)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one

Guidance literature:: (S)-6-((2S,3S)-3-phenyloxiran-2-yl)-5,6-dihydro-2H-pyran-2-one; With perchloric acid; water; for 1h;

With sodium hydrogencarbonate; In water; at 20 ℃; Overall yield = 94 %;
DOI:10.1021/acs.jnatprod.6b00386

Reference yield:

: 122046-62-2
(S)-goniothalamin

: 1152589-20-2
(6S,7R,8S)-(-)-7-epi-goniodiol

: 474097-60-4
(6S)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane

2.1: perchloric acid; water / 1 h

2.2: 20 °C

With perchloric acid; water; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1021/acs.jnatprod.6b00386

Reference yield:

: 14371-10-9
(E)-3-phenylpropenal

: 1152589-20-2
(6S,7R,8S)-(-)-7-epi-goniodiol

: 474097-60-4
(6S)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-5,6-dihydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: titanium tetrachloride; titanium(IV) isopropylate; silver(l) oxide; (S)-2,2'-dihydroxy-1,1'-binaphthyl / dichloromethane / 48 h / -15 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 2 h / 0 °C

3.1: Grubbs catalyst first generation / dichloromethane / 6 h / Reflux

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane

5.1: perchloric acid; water / 1 h

5.2: 20 °C

With (S)-2,2'-dihydroxy-1,1'-binaphthyl; Grubbs catalyst first generation; titanium(IV) isopropylate; perchloric acid; water; titanium tetrachloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; silver(l) oxide; In dichloromethane;
DOI:10.1021/acs.jnatprod.6b00386