Ethyl 2-fluoro-3-hydroxybenzoate

Base Information

• Chemical Name: Ethyl 2-fluoro-3-hydroxybenzoate
• CAS No.: 105836-28-0
• Molecular Formula: C9H9FO3
• Molecular Weight: 184.16400
• Hs Code.: 2918290090
• DSSTox Substance ID: DTXSID00547647
• Wikidata: Q82425983
• Mol file: 105836-28-0.mol

Synonyms:ethyl 2-fluoro-3-hydroxybenzoate;105836-28-0;SCHEMBL7728983;ethyl2-fluoro-3-hydroxybenzoate;DTXSID00547647;AMY14714;2-Fluoro-3-hydroxy-benzoic acid ethyl ester

Chemical Property of Ethyl 2-fluoro-3-hydroxybenzoate

Chemical Property:

• Boiling Point: 293.8±25.0 °C(Predicted)
• PKA: 7.94±0.10(Predicted)
• PSA: 46.53000
• Density: 1.257±0.06 g/cm3(Predicted)
• LogP: 1.70800
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 184.05357231
• Heavy Atom Count: 13
• Complexity: 184

Purity/Quality:

95% ^*data from raw suppliers

Ethyl2-fluoro-3-hydroxybenzoate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=C(C(=CC=C1)O)F

Technology Process of Ethyl 2-fluoro-3-hydroxybenzoate

There total 1 articles about Ethyl 2-fluoro-3-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-carboethoxy-3,3-difluoro-7-oxabicyclo<2.2.1>hept-5-ene (105836-30-4,105836-31-5) → ethyl 2-fluoro-3-hydroxybenzoate (105836-28-0)

Guidance literature:

With tetrabutyl ammonium fluoride; for 2h; Heating;

DOI:10.1021/jo00378a028

upstream raw materials:

2-carboethoxy-3,3-difluoro-7-oxabicyclo<2.2.1>hept-5-ene