5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine

Base Information

• Chemical Name: 5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine
• CAS No.: 20939-90-6
• Molecular Formula: C₁₄H₁₆N₂OS₂
• Molecular Weight: 292.426
• Mol file: 20939-90-6.mol

Synonyms:

Chemical Property of 5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine

There total 1 articles about 5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dimethyl-5-(2-hydroxyethyl)thiazolium iodide (16311-69-6) + phenyl isothiocyanate (103-72-0) → 5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine (20939-90-6)

Guidance literature:

Multistep reaction; (i) Et₃N, DMF, (ii) /BRN= 471392/;

DOI:10.1016/S0040-4039(00)76311-8

Reference yield:

5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine (20939-90-6) → 5-(2-hydroxy-ethyl)-3,4-dimethyl-thiazolidine-2-carbothioic acid anilide (21164-14-7)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1016/S0040-4039(00)76311-8

Reference yield:

5-(2-hydroxy-ethyl)-3,4-dimethyl-2-(phenyl-thiocarbamoyl)-thiazolium betaine (20939-90-6) → 6-(2-hydroxy-ethyl)-4,5-dimethyl-2-phenylimino-4H-[1,4]thiazin-3-one (20940-06-1)

Guidance literature:

With sodium hydroxide; In ethanol; for 1h; Ambient temperature;

DOI:10.1248/cpb.22.293

upstream raw materials:

3,4-dimethyl-5-(2-hydroxyethyl)thiazolium iodide

phenyl isothiocyanate

Downstream raw materials:

5-(2-hydroxy-ethyl)-3,4-dimethyl-thiazolidine-2-carbothioic acid anilide

6-(2-hydroxy-ethyl)-4,5-dimethyl-2-phenylimino-4H-[1,4]thiazin-3-one