(+)-(S)-allyl-p-toluenesulphinamide

Base Information

• Chemical Name: (+)-(S)-allyl-p-toluenesulphinamide
• CAS No.: 111289-38-4
• Molecular Formula: C₁₀H₁₃NOS
• Molecular Weight: 195.285
• Mol file: 111289-38-4.mol

Synonyms:

Chemical Property of (+)-(S)-allyl-p-toluenesulphinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-(S)-allyl-p-toluenesulphinamide

There total 7 articles about (+)-(S)-allyl-p-toluenesulphinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate (1517-82-4) + 1-amino-2-propene (107-11-9,30551-89-4) → (+)-(S)-allyl-p-toluenesulphinamide (40723-30-6,116560-12-4,111289-38-4)

Guidance literature:

1-amino-2-propene; With n-butyllithium;

(1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.3987/COM-00-S(I)31

Reference yield: 67.0%

1,2:5,6-Di-O-isopropylidene-α-D-glucofuranosyl (-)-(S)-p-toluenesulfinate (79378-71-5,79378-73-7,82079-38-7,82079-39-8) + 1-amino-2-propene (107-11-9,30551-89-4) → (+)-(S)-allyl-p-toluenesulphinamide (40723-30-6,116560-12-4,111289-38-4)

Guidance literature:

1-amino-2-propene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h; Inert atmosphere;

1,2:5,6-Di-O-isopropylidene-α-D-glucofuranosyl (-)-(S)-p-toluenesulfinate; In tetrahydrofuran; at -78 ℃; for 0.0833333h; Inert atmosphere;

DOI:10.1039/c2ob07132k

Reference yield: 63.0%

methyl p-toluene sulfinate (672-78-6) + 1-amino-2-propene (107-11-9,30551-89-4) → N-allyl-4-methylbenzenesulfinamide (111289-38-4,116560-12-4,40723-30-6)

Guidance literature:

With nickel dichloride; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In tetrahydrofuran; at 100 ℃; for 15h; Inert atmosphere;

DOI:10.1016/j.tetlet.2019.151260

upstream raw materials:

Ethyl p-toluenesulfinate

1-amino-2-propene

4-methylbenzenesulfinyl chloride

methyl p-toluene sulfinate

Downstream raw materials:

N,N-diallyl-4-methylbenzenesulfinamide

4-methyl-N-(2-propenyl)benzenesulfonamide

t-butyl [(S)-p-tolylsulphinyl]acetate

N,N-diallyltoluene-p-sulphinamide