C₁₅H₈Cl₃N₅

Base Information

• Chemical Name: C₁₅H₈Cl₃N₅
• CAS No.: 1346428-32-7
• Molecular Formula: C₁₅H₈Cl₃N₅
• Molecular Weight: 364.621
• Mol file: 1346428-32-7.mol

Synonyms:

Chemical Property of C₁₅H₈Cl₃N₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₈Cl₃N₅

There total 1 articles about C₁₅H₈Cl₃N₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(tributylstannyl)-1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole (1213234-84-4) → C15H8Cl3N5 (1346428-32-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; for 2.5h; Reflux; Large scale reaction;

DOI:10.1016/j.bmcl.2011.08.073

Reference yield:

C15H8Cl3N5 (1346428-32-7) → C15H9Cl3N8

Guidance literature:

With sodium azide; ammonium chloride; In N,N-dimethyl-formamide; at 105 ℃; for 2h;

DOI:10.1016/j.bmcl.2011.08.073

Reference yield:

C15H8Cl3N5 (1346428-32-7) → C17H11Cl3N8O2 (1346427-88-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 2 h / 105 °C

2: triethylamine / tetrahydrofuran / 2 h / Reflux

3: methanol; sodium hydroxide / tetrahydrofuran / 3 h / 20 °C

With methanol; sodium azide; ammonium chloride; triethylamine; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.08.073

upstream raw materials:

4-(tributylstannyl)-1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole

Downstream raw materials:

C₁₇H₁₁Cl₃N₈O₂