N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide

Base Information

Chemical Name:N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide
CAS No.:235097-83-3
Molecular Formula:C₃₉H₄₆FN₅O₆
Molecular Weight:699.823
Hs Code.:

N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide

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Chemical Property of N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide

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Technology Process of N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide

There total 8 articles about N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-fluorophenyl)-4-(t-butyldimethylsilyloxy)butyronitrile

: 235097-83-3,235097-84-4,195718-05-9
N-methyl-N-(4-(4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(4-fluorophenyl)butyl)-3,4,5-trimethoxybenzamide

Guidance literature:: Multi-step reaction with 6 steps

1: aluminum nickel / ethanol

2: ammonium chloride; sodium hydrogencarbonate; sodium carbonate / water; ethyl acetate

3: N-methyl-acetamide

4: ammonium fluoride / methanol

5: hydrogenchloride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine / dichloromethane

With hydrogenchloride; ammonium fluoride; ammonium chloride; sodium hydrogencarbonate; sodium carbonate; N-ethyl-N,N-diisopropylamine; aluminum nickel; In N-methyl-acetamide; methanol; ethanol; dichloromethane; water; ethyl acetate;