C₈H₁₁N₃O₂

Base Information

• Chemical Name: C₈H₁₁N₃O₂
• CAS No.: 1344669-96-0
• Molecular Formula: C₈H₁₁N₃O₂
• Molecular Weight: 181.194
• Mol file: 1344669-96-0.mol

Synonyms:

Chemical Property of C₈H₁₁N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₈H₁₁N₃O₂

There total 2 articles about C₈H₁₁N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H9N3O4 → C8H11N3O2 (1344669-96-0)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In ethanol; water; under 2585.81 Torr;

DOI:10.1016/j.bmcl.2011.08.071

Reference yield:

ethyl 2-(pyridazin-3-yl)acetate (1260885-52-6) → C8H11N3O2 (1344669-96-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite / water; acetic acid / 0 - 20 °C

2: hydrogenchloride; palladium 10% on activated carbon; hydrogen / ethanol; water / 2585.81 Torr

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium nitrite; In ethanol; water; acetic acid;

DOI:10.1016/j.bmcl.2011.08.071

Reference yield:

C8H11N3O2 (1344669-96-0) → C16H14FN3O2 (1344669-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane

2: trichlorophosphate / Heating

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In dichloromethane;

DOI:10.1016/j.bmcl.2011.08.071

upstream raw materials:

ethyl 2-(pyridazin-3-yl)acetate

Downstream raw materials:

C₁₆H₁₄FN₃O₂

7-(2-fluorobenzyl)imidazo[1,5-b]pyridazine-5-carbonitrile

C₁₆H₁₀F₄N₆

7-(2-Fluorobenzyl)imidazo[1,5-b]pyridazine-5-carboximidohydrazide