1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester)

Base Information

• Chemical Name: 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester)
• CAS No.: 1427040-41-2
• Molecular Formula: C₉₀H₁₄₉N₁₃O₂₁
• Molecular Weight: 1749.25
• Mol file: 1427040-41-2.mol

Synonyms:

Chemical Property of 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester)

There total 1 articles about 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[7-N-[2-aminoethyl]-9-amino-6-oxo-7-azanonyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethylester) (1427040-38-7) + N14-methyl-7,14-diaza-8,15-dioxo-18-methyloxycarbonyl-18-benzyloxycarbonylamino-18-(S)-octadecanoic acid (1427040-28-5) → 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester) (1427040-41-2)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 96.5h;

DOI:10.1021/jm301831f

Reference yield:

1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-methyloxycarbonyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethyl ester) (1427040-41-2) → 1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-carboxyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic(1,1-dimethylethyl ester) (1427040-43-4)

Guidance literature:

With sodium hydroxide; In methanol; water; at 20 ℃; for 5h; pH=12;

DOI:10.1021/jm301831f

upstream raw materials:

1-[7-N-[2-aminoethyl]-9-amino-6-oxo-7-azanonyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic (1,1-dimethylethylester)

N¹⁴-methyl-7,14-diaza-8,15-dioxo-18-methyloxycarbonyl-18-benzyloxycarbonylamino-18-(S)-octadecanoic acid

Downstream raw materials:

1-[5-[[N,N′-bis[3,10,17-triaza-4,11,18-trioxo-21-carboxyl-21-benzyloxycarbonyl-N-methylaminoeinecosane]]aminocarbonyl]pentyl]-1,4,7,10-tetraazacyclododecane-4,7,10-triacetic(1,1-dimethylethyl ester)