Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

(5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one

Base Information Edit
  • Chemical Name:(5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one
  • CAS No.:201667-93-8
  • Molecular Formula:C34H48O7
  • Molecular Weight:568.751
  • Hs Code.:
  • Mol file:201667-93-8.mol
(5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one

Synonyms:

Suppliers and Price of (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 0 raw suppliers
Chemical Property of (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one Edit
Chemical Property:
Purity/Quality:
Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
Technology Process of (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one

There total 34 articles about (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 18 steps
1: 1) (COCl)2, DMSO, 2) NEt3 / 1) CH2Cl2, -78 deg C, 15 min, 2) CH2Cl2, 0 deg C, 20 min
2: 88 percent / BuLi / tetrahydrofuran; CH2Cl2 / 1 h / -78 °C
3: 98 percent / H2 / Lindlar catalyst / methanol / 48 h / 760 Torr / Ambient temperature
4: 100 percent / DMAP, NEt3 / CH2Cl2 / 15 h / Ambient temperature
5: 63 percent / DDQ / CH2Cl2; H2O / 0.5 h / 0 °C
6: 90 percent / pyridinium dichromate, 4 Angstroem molecular sieves / CH2Cl2 / 2 h / Ambient temperature
7: NaClO2, NaH2PO4*2H2O, 2-methyl-2-butene / 2-methyl-propan-2-ol; H2O / 1.5 h / 0 °C
8: 34.0 mg / KOH / methanol; H2O / 24 h / Ambient temperature
9: 1) 2,4,6-trichlorobenzoyl chloride, NEt3, 2) DMAP / 1) toluene, room temperature, 18 h, 2) toluene, room temperature, 1 h
11: 92 percent / LiAlH4 / diethyl ether / 1.5 h / 0 - 20 °C
12: 95 percent / KH, TBAI / tetrahydrofuran / 2 h / Heating
13: 75 percent / 1 M aq. HCl / methanol / 3 h / Ambient temperature
14: 71 percent / NEt3, DMAP / CH2Cl2 / 26 h / Ambient temperature
15: 100 percent / K2CO3 / methanol / 2.5 h / Ambient temperature
16: 76 percent / dimethylsulfoxide / 4 h / Ambient temperature
17: 95 percent / H2 / Lindlar catalyst / benzene / 0.5 h / 760 Torr / Ambient temperature
18: 1) (COCl)2, DMSO, 2) NEt3 / 1) CH2Cl2, -78 deg C, 1 h, 2) CH2Cl2, 0 deg C, 30 min
With hydrogenchloride; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; lithium aluminium tetrahydride; dipyridinium dichromate; n-butyllithium; 2-methyl-but-2-ene; oxalyl dichloride; 4 A molecular sieve; 2,4,6-trichlorobenzoyl chloride; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; Lindlar's catalyst; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; dimethyl sulfoxide; tert-butyl alcohol; benzene;
DOI:10.1016/S0040-4020(97)10253-8
Guidance literature:
Multi-step reaction with 17 steps
1: 88 percent / BuLi / tetrahydrofuran; CH2Cl2 / 1 h / -78 °C
2: 98 percent / H2 / Lindlar catalyst / methanol / 48 h / 760 Torr / Ambient temperature
3: 100 percent / DMAP, NEt3 / CH2Cl2 / 15 h / Ambient temperature
4: 63 percent / DDQ / CH2Cl2; H2O / 0.5 h / 0 °C
5: 90 percent / pyridinium dichromate, 4 Angstroem molecular sieves / CH2Cl2 / 2 h / Ambient temperature
6: NaClO2, NaH2PO4*2H2O, 2-methyl-2-butene / 2-methyl-propan-2-ol; H2O / 1.5 h / 0 °C
7: 34.0 mg / KOH / methanol; H2O / 24 h / Ambient temperature
8: 1) 2,4,6-trichlorobenzoyl chloride, NEt3, 2) DMAP / 1) toluene, room temperature, 18 h, 2) toluene, room temperature, 1 h
10: 92 percent / LiAlH4 / diethyl ether / 1.5 h / 0 - 20 °C
11: 95 percent / KH, TBAI / tetrahydrofuran / 2 h / Heating
12: 75 percent / 1 M aq. HCl / methanol / 3 h / Ambient temperature
13: 71 percent / NEt3, DMAP / CH2Cl2 / 26 h / Ambient temperature
14: 100 percent / K2CO3 / methanol / 2.5 h / Ambient temperature
15: 76 percent / dimethylsulfoxide / 4 h / Ambient temperature
16: 95 percent / H2 / Lindlar catalyst / benzene / 0.5 h / 760 Torr / Ambient temperature
17: 1) (COCl)2, DMSO, 2) NEt3 / 1) CH2Cl2, -78 deg C, 1 h, 2) CH2Cl2, 0 deg C, 30 min
With hydrogenchloride; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; lithium aluminium tetrahydride; dipyridinium dichromate; n-butyllithium; 2-methyl-but-2-ene; oxalyl dichloride; 4 A molecular sieve; 2,4,6-trichlorobenzoyl chloride; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; Lindlar's catalyst; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; dimethyl sulfoxide; tert-butyl alcohol; benzene;
DOI:10.1016/S0040-4020(97)10253-8
Guidance literature:
Multi-step reaction with 22 steps
1: CH2Cl2; hexane / 17 h / Ambient temperature
2: 1.18 g / NEt3, DMAP / CH2Cl2 / 17 h / Ambient temperature
3: 93 percent / p-toluenesulfonic acid monohydrate / acetone / 36 h / Ambient temperature
4: 87 percent / H2 / Pd-C / ethanol / 24 h / 760 Torr / Ambient temperature
5: 1) (COCl)2, DMSO, 2) NEt3 / 1) CH2Cl2, -78 deg C, 15 min, 2) CH2Cl2, 0 deg C, 20 min
6: 88 percent / BuLi / tetrahydrofuran; CH2Cl2 / 1 h / -78 °C
7: 98 percent / H2 / Lindlar catalyst / methanol / 48 h / 760 Torr / Ambient temperature
8: 100 percent / DMAP, NEt3 / CH2Cl2 / 15 h / Ambient temperature
9: 63 percent / DDQ / CH2Cl2; H2O / 0.5 h / 0 °C
10: 90 percent / pyridinium dichromate, 4 Angstroem molecular sieves / CH2Cl2 / 2 h / Ambient temperature
11: NaClO2, NaH2PO4*2H2O, 2-methyl-2-butene / 2-methyl-propan-2-ol; H2O / 1.5 h / 0 °C
12: 34.0 mg / KOH / methanol; H2O / 24 h / Ambient temperature
13: 1) 2,4,6-trichlorobenzoyl chloride, NEt3, 2) DMAP / 1) toluene, room temperature, 18 h, 2) toluene, room temperature, 1 h
15: 92 percent / LiAlH4 / diethyl ether / 1.5 h / 0 - 20 °C
16: 95 percent / KH, TBAI / tetrahydrofuran / 2 h / Heating
17: 75 percent / 1 M aq. HCl / methanol / 3 h / Ambient temperature
18: 71 percent / NEt3, DMAP / CH2Cl2 / 26 h / Ambient temperature
19: 100 percent / K2CO3 / methanol / 2.5 h / Ambient temperature
20: 76 percent / dimethylsulfoxide / 4 h / Ambient temperature
21: 95 percent / H2 / Lindlar catalyst / benzene / 0.5 h / 760 Torr / Ambient temperature
22: 1) (COCl)2, DMSO, 2) NEt3 / 1) CH2Cl2, -78 deg C, 1 h, 2) CH2Cl2, 0 deg C, 30 min
With hydrogenchloride; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; lithium aluminium tetrahydride; dipyridinium dichromate; n-butyllithium; 2-methyl-but-2-ene; oxalyl dichloride; 4 A molecular sieve; 2,4,6-trichlorobenzoyl chloride; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; potassium carbonate; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; Lindlar's catalyst; In tetrahydrofuran; methanol; diethyl ether; ethanol; hexane; dichloromethane; water; dimethyl sulfoxide; acetone; tert-butyl alcohol; benzene;
DOI:10.1016/S0040-4020(97)10253-8
Post RFQ for Price