(S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide

Base Information

Chemical Name:(S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide
CAS No.:1159489-03-8
Molecular Formula:C₃₀H₂₈F₄N₄O₃S
Molecular Weight:600.637
Hs Code.:

(S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide

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Technology Process of (S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide

There total 1 articles about (S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1159489-45-8
C₂₃H₂₁BrF₄N₄O

: 149104-88-1
4-methanesulphonylphenylboronic acid

: 1159489-03-8
(S)-N-((S)-cyano-(4-cyano-2-fluoro-benzyl)-methyl)-3-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-butyramide

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃;
DOI:10.1016/j.bmcl.2010.10.015