(1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate

Base Information

• Chemical Name: (1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate
• CAS No.: 1160525-89-2
• Molecular Formula: C₁₆H₂₇O₅P
• Molecular Weight: 330.361
• Mol file: 1160525-89-2.mol

Synonyms:

Chemical Property of (1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate

There total 1 articles about (1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diisopropyl hydrogenphosphonate (1809-20-7) + (R)-2-benzyloxypropanal (53346-05-7,41954-96-5,81445-44-5,81445-45-6) → (1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate (1160525-89-2) + (1R,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate (1160525-88-1)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1039/b821829c

Reference yield:

(1S,2R)-diisopropyl 2-benzyloxy-1-hydroxypropylphosphonate (1160525-89-2) → C10H15O5P

Guidance literature:

With trimethylsilyl bromide; allyl-trimethyl-silane; In 1,2-dichloro-ethane; at 50 ℃; for 17h;

DOI:10.1039/b821829c

upstream raw materials:

diisopropyl hydrogenphosphonate

(R)-2-benzyloxypropanal