(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Base Information

Chemical Name:(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one
CAS No.:132248-59-0
Molecular Formula:C₁₅H₁₁NO₄
Molecular Weight:269.257
Hs Code.:

Synonyms:

Suppliers and Price of (2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(2E)-1-(4-Hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one
500mg
$ 95.00

Total 2 raw suppliers

Chemical Property of (2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

(2E)-1-(4-Hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

General Description (2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one **(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one** is a chalcone derivative with potential cytotoxic and nematicidal properties. While the first abstract highlights the cytotoxic activity of Mannich base derivatives of chalcones (though not this specific compound), the second abstract confirms its synthesis as part of a series of chalcones evaluated for bioactivity against root-knot nematodes (*Meloidogyne javanica*). This suggests that the compound may serve as a scaffold for developing agents with pesticidal or pharmacological applications, though further studies would be needed to elucidate its specific mechanisms or efficacy. **Other names**: - 3-(4-Nitrophenyl)-1-(4-hydroxyphenyl)-2-propen-1-one - (E)-1-(4-Hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one - 4'-Hydroxy-4-nitrochalcone

Technology Process of (2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

There total 5 articles about (2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 555-16-8
4-nitrobenzaldehdye

: 99-93-4
4-Hydroxyacetophenone

: 132248-59-0,38270-11-0
(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Guidance literature:: With water; sodium hydroxide; In ethanol; at 5 - 25 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2018.09.016

Reference yield: 55.5%

: (E)-3-(4-Nitro-phenyl)-1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-propenone

: 132248-59-0,38270-11-0
(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Guidance literature:: With hydrogenchloride; In ethanol; at 28 ℃; for 4h;
DOI:10.1021/jm0101747

Reference yield:

: 16162-69-9
1-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone

: 132248-59-0,38270-11-0
(2E)-1-(4-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / methanol / 28 °C

2: 55.5 percent / aq. HCl / ethanol / 4 h / 28 °C

With hydrogenchloride; sodium hydroxide; In methanol; ethanol;
DOI:10.1021/jm0101747