cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide)

Base Information

• Chemical Name: cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide)
• CAS No.: 116210-90-3
• Molecular Formula: C₂₀H₃₀N₂O₂
• Molecular Weight: 330.47
• Mol file: 116210-90-3.mol

Synonyms:

Chemical Property of cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide)

There total 5 articles about cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

morpholine (110-91-8,99108-56-2) + N-(2-cyclohexyl-2-phenylacetyl)aziridine (116210-94-7) → cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide) (116210-90-3)

Guidance literature:

In acetone; for 15h; Heating;

DOI:10.1021/jm00120a007

Reference yield:

cyclohexyl-phenyl-acetyl chloride (49802-71-3) → cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide) (116210-90-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / NaOH / H₂O; CH₂Cl₂ / 2 h / Ambient temperature

2: 3 h / 90 °C

With sodium hydroxide; In dichloromethane; water;

DOI:10.1021/jm00120a007

Reference yield:

2-cyclohexyl-2-phenylacetic acid (3894-09-5,51019-55-7) → cyclohexyl-phenyl-acetic acid-(2-morpholino-ethylamide) (116210-90-3)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / benzene / 3 h / 70 °C

2: 93 percent / NaOH / H₂O; CH₂Cl₂ / 2 h / Ambient temperature

3: 3 h / 90 °C

With sodium hydroxide; thionyl chloride; In dichloromethane; water; benzene;

DOI:10.1021/jm00120a007

upstream raw materials:

4-(2-AMINOETHYL)MORPHOLINE

cyclohexyl-phenyl-acetyl chloride

morpholine

N-(2-cyclohexyl-2-phenylacetyl)aziridine

Refernces