2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester

Base Information

Chemical Name:2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester
CAS No.:105897-88-9
Molecular Formula:C₂₁H₃₂O₄S
Molecular Weight:380.549
Hs Code.:

Synonyms:

Suppliers and Price of 2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester

There total 17 articles about 2-Undecenoic acid, 8,11-dihydroxy-5-(1-methylethyl)-2-(phenylthio)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 105897-85-6
(R)-3-(1-methylethyl)-6-oxoheptanal dimethylacetal

: 105897-88-9
(E)-(R)-8,11-Dihydroxy-5-isopropyl-2-phenylsulfanyl-undec-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 11 steps

1: 1.) NaH / 1.) dioxane, MeOH, reflux; 2.) reflux, 90 min

2: 62 percent / 1.) KOH / methanol; H₂O / 2 h / Heating

3: LiAlH₄ / diethyl ether / 1 h / below 10 deg C

4: EtN(i-Pr)2 / CH₂Cl₂ / 24 h / Heating

5: OsO₄, NaIO₄ / diethyl ether; H₂O / 7 h

6: LiAlH₄ / diethyl ether / 0.5 h / below 10 deg C

7: pyridine / Ambient temperature

8: 75 percent AcOH / 1 h / 30 °C

9: 1.) LDA / 1.) THF, below -60 deg C, 20 min; 2.) THF, below -60 deg C, 30 min

10: NaOAc / 0.67 h / 130 °C

11: MeONa / methanol

With pyridine; potassium hydroxide; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; sodium methylate; sodium acetate; sodium hydride; acetic acid; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)86874-5

Reference yield:

: 105897-86-7
(R)-3-(1-methylethyl)-6-oxo-9-decenal dimethylacetal

: 105897-88-9
(E)-(R)-8,11-Dihydroxy-5-isopropyl-2-phenylsulfanyl-undec-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 9 steps

1: LiAlH₄ / diethyl ether / 1 h / below 10 deg C

2: EtN(i-Pr)2 / CH₂Cl₂ / 24 h / Heating

3: OsO₄, NaIO₄ / diethyl ether; H₂O / 7 h

4: LiAlH₄ / diethyl ether / 0.5 h / below 10 deg C

5: pyridine / Ambient temperature

6: 75 percent AcOH / 1 h / 30 °C

7: 1.) LDA / 1.) THF, below -60 deg C, 20 min; 2.) THF, below -60 deg C, 30 min

8: NaOAc / 0.67 h / 130 °C

9: MeONa / methanol

With pyridine; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; sodium methylate; sodium acetate; acetic acid; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)86874-5

Reference yield:

: 112193-61-0,115042-30-3,115042-31-4
(R)-2-Allyl-6-(2,2-dimethoxy-ethyl)-7-methyl-3-oxo-octanoic acid methyl ester

: 105897-88-9
(E)-(R)-8,11-Dihydroxy-5-isopropyl-2-phenylsulfanyl-undec-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 10 steps

1: 62 percent / 1.) KOH / methanol; H₂O / 2 h / Heating

2: LiAlH₄ / diethyl ether / 1 h / below 10 deg C

3: EtN(i-Pr)2 / CH₂Cl₂ / 24 h / Heating

4: OsO₄, NaIO₄ / diethyl ether; H₂O / 7 h

5: LiAlH₄ / diethyl ether / 0.5 h / below 10 deg C

6: pyridine / Ambient temperature

7: 75 percent AcOH / 1 h / 30 °C

8: 1.) LDA / 1.) THF, below -60 deg C, 20 min; 2.) THF, below -60 deg C, 30 min

9: NaOAc / 0.67 h / 130 °C

10: MeONa / methanol

With pyridine; potassium hydroxide; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; sodium methylate; sodium acetate; acetic acid; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)86874-5