CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)

Base Information

• Chemical Name: CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)
• CAS No.: 1356397-56-2
• Molecular Formula: C₃₇H₃₁Cl₂CuFN₆O₃
• Molecular Weight: 761.142
• Mol file: 1356397-56-2.mol

Synonyms:

Chemical Property of CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)

There total 1 articles about CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.2%

copper(II) choride dihydrate + 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid (70458-96-7) + 4’-(4-chlorophenyl)-2,2’:6’,2’’-terpyridine (89972-75-8) → CuCl(1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxylate)(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine) (1356397-56-2)

Guidance literature:

With CH₃ONa; In methanol; soln. of CuCl2 added to soln. of terpyridine followed by addition of norfloxacin in presence of CH3ONa, pH adjusted to 6.8, soln. refluxed for 2h on water bath; concd., solid obtained washed (ether/hexane), dried (vac. desiccator); elem. anal.;

DOI:10.1016/j.jorganchem.2011.11.022

upstream raw materials:

1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid

4’-(4-chlorophenyl)-2,2’:6’,2’’-terpyridine