C₃₆H₄₇N₅O₂S

Base Information

• Chemical Name: C₃₆H₄₇N₅O₂S
• CAS No.: 1397458-19-3
• Molecular Formula: C₃₆H₄₇N₅O₂S
• Molecular Weight: 613.867
• Mol file: 1397458-19-3.mol

Synonyms:

Chemical Property of C₃₆H₄₇N₅O₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₇N₅O₂S

There total 7 articles about C₃₆H₄₇N₅O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-ethyl 4-(tert-butoxycarbonylamino)-4-cyclohexylbutanoate → C36H47N5O2S (1397458-19-3)

Guidance literature:

Multi-step reaction with 6 steps

1: water; lithium hydroxide / tetrahydrofuran

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine

3: trifluoroacetic acid / dichloromethane

4: sodium tris(acetoxy)borohydride

5: palladium 10% on activated carbon; hydrogen / ethyl acetate

6: ethanol / Reflux

With palladium 10% on activated carbon; water; hydrogen; sodium tris(acetoxy)borohydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate;

DOI:10.1016/j.bmcl.2012.07.043

Reference yield:

4-tert-butoxycarbonylamino-4-cyclohexyl-butyric acid (876761-25-0) → C36H47N5O2S (1397458-19-3)

Guidance literature:

Multi-step reaction with 5 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine

2: trifluoroacetic acid / dichloromethane

3: sodium tris(acetoxy)borohydride

4: palladium 10% on activated carbon; hydrogen / ethyl acetate

5: ethanol / Reflux

With palladium 10% on activated carbon; hydrogen; sodium tris(acetoxy)borohydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In ethanol; dichloromethane; ethyl acetate;

DOI:10.1016/j.bmcl.2012.07.043

Reference yield:

C22H37N3OS → C36H47N5O2S (1397458-19-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tris(acetoxy)borohydride

2: palladium 10% on activated carbon; hydrogen / ethyl acetate

3: ethanol / Reflux

With palladium 10% on activated carbon; hydrogen; sodium tris(acetoxy)borohydride; In ethanol; ethyl acetate;

DOI:10.1016/j.bmcl.2012.07.043

upstream raw materials:

4-tert-butoxycarbonylamino-4-cyclohexyl-butyric acid

bromocyane

C₁₇H₂₉NO₄