C₁₉H₂₉NO₂

Base Information

• Chemical Name: C₁₉H₂₉NO₂
• CAS No.: 1334335-25-9
• Molecular Formula: C₁₉H₂₉NO₂
• Molecular Weight: 303.445
• Mol file: 1334335-25-9.mol

Synonyms:

Chemical Property of C₁₉H₂₉NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₉NO₂

There total 5 articles about C₁₉H₂₉NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-benzyloxybenzaldehyde (4397-53-9) → C19H29NO2 (1334335-25-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: tetrahydrofuran / 0.25 h / 40 °C

2.1: sodium hydride / N,N-dimethyl-formamide

2.2: 1 h / 20 °C

3.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h / Reflux

4.1: palladium 10% on activated carbon; hydrogen / ethanol / 15 h / 20 °C / 2250.23 Torr

5.1: potassium carbonate / N,N-dimethyl-formamide / 20 h / 20 °C

6.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 5 h / 60 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium 10% on activated carbon; hydrogen; sodium hydride; potassium carbonate; potassium iodide; In tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.07.006

Reference yield:

C20H22O2 (1334335-32-8) → C19H29NO2 (1334335-25-9)

Guidance literature:

Multi-step reaction with 4 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h / Reflux

2: palladium 10% on activated carbon; hydrogen / ethanol / 15 h / 20 °C / 2250.23 Torr

3: potassium carbonate / N,N-dimethyl-formamide / 20 h / 20 °C

4: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 5 h / 60 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; potassium iodide; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.07.006

Reference yield:

C18H20O2 → C19H29NO2 (1334335-25-9)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 15 h / 20 °C / 2250.23 Torr

2: potassium carbonate / N,N-dimethyl-formamide / 20 h / 20 °C

3: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 5 h / 60 °C

With palladium 10% on activated carbon; hydrogen; potassium carbonate; potassium iodide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.07.006

upstream raw materials:

p-benzyloxybenzaldehyde

C₂₀H₂₂O₂

C₁₁H₁₄O₂

(+/-)-1-(4-benzyloxyphenyl)but-3-en-1-ol