C₃₅H₃₅ClF₃N₃O₆

Base Information

Chemical Name:C₃₅H₃₅ClF₃N₃O₆
CAS No.:1416976-30-1
Molecular Formula:C₃₅H₃₅ClF₃N₃O₆
Molecular Weight:686.128
Hs Code.:

C<sub>35</sub>H<sub>35</sub>ClF<sub>3</sub>N<sub>3</sub>O<sub>6</sub>

Synonyms:

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Chemical Property of C₃₅H₃₅ClF₃N₃O₆

Chemical Property:

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Technology Process of C₃₅H₃₅ClF₃N₃O₆

There total 12 articles about C₃₅H₃₅ClF₃N₃O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416976-11-8
C₄₀H₄₃ClF₃N₃O₈

: 1416976-30-1
C₃₅H₃₅ClF₃N₃O₆

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 20 ℃;
DOI:10.1016/j.bmcl.2012.10.095

Reference yield:

: 1311412-04-0
C₃₁H₄₃BrF₃NO₆Si

: 1416976-30-1
C₃₅H₃₅ClF₃N₃O₆

Guidance literature:: Multi-step reaction with 4 steps

1: HATU; triethylamine / 20 °C

2: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 50 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; 1,4-dioxane / 110 °C

4: chloro-trimethyl-silane; sodium iodide / acetonitrile / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; chloro-trimethyl-silane; tetrabutyl ammonium fluoride; sodium carbonate; triethylamine; HATU; sodium iodide; In 1,4-dioxane; water; N,N-dimethyl-formamide; acetonitrile; 3: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.10.095

Reference yield:

: 1416975-90-0
C₂₅H₂₉BrF₃NO₆

: 1416976-30-1
C₃₅H₃₅ClF₃N₃O₆

Guidance literature:: Multi-step reaction with 5 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C

2: HATU; triethylamine / 20 °C

3: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 50 °C

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; 1,4-dioxane / 110 °C

5: chloro-trimethyl-silane; sodium iodide / acetonitrile / 20 °C

With 1H-imidazole; tetrakis(triphenylphosphine) palladium⁽⁰⁾; chloro-trimethyl-silane; tetrabutyl ammonium fluoride; sodium carbonate; triethylamine; HATU; sodium iodide; In 1,4-dioxane; water; N,N-dimethyl-formamide; acetonitrile; 4: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.10.095