FIPRL-OMe

Base Information

• Chemical Name: FIPRL-OMe
• CAS No.: 219133-69-4
• Molecular Formula: C₃₃H₅₄N₈O₆
• Molecular Weight: 658.842
• Mol file: 219133-69-4.mol

Synonyms:

Chemical Property of FIPRL-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of FIPRL-OMe

There total 10 articles about FIPRL-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(tert-butoxycarbonyl)-L-proline (15761-39-4,59433-50-0) → FIPRL-OMe (219133-69-4)

Guidance literature:

Multi-step reaction with 7 steps

1: DCC; HOSu / dimethylformamide

2: TFA

3: DCC; HOSu / dimethylformamide

4: TFA

5: DCC; HOSu / dimethylformamide

6: TFA

7: TFMSA

With 1-hydroxy-pyrrolidine-2,5-dione; trifluorormethanesulfonic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In N,N-dimethyl-formamide; 1: Condensation / 2: deprotection / 3: Condensation / 4: deprotection / 5: Condensation / 6: deprotection / 7: deprotection;

DOI:10.1271/bbb.62.1875

Reference yield:

(S)-Leu-OMe (2666-93-5) → FIPRL-OMe (219133-69-4)

Guidance literature:

Multi-step reaction with 9 steps

1: DCC; HOSu / dimethylformamide

2: TFA

3: DCC; HOSu / dimethylformamide

4: TFA

5: DCC; HOSu / dimethylformamide

6: TFA

7: DCC; HOSu / dimethylformamide

8: TFA

9: TFMSA

With 1-hydroxy-pyrrolidine-2,5-dione; trifluorormethanesulfonic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In N,N-dimethyl-formamide; 1: Condensation / 2: deprotection / 3: Condensation / 4: deprotection / 5: Condensation / 6: deprotection / 7: Condensation / 8: deprotection / 9: deprotection;

DOI:10.1271/bbb.62.1875

Reference yield:

Boc-Arg(Tos)-OH (13836-37-8) → FIPRL-OMe (219133-69-4)

Guidance literature:

Multi-step reaction with 9 steps

1: DCC; HOSu / dimethylformamide

2: TFA

3: DCC; HOSu / dimethylformamide

4: TFA

5: DCC; HOSu / dimethylformamide

6: TFA

7: DCC; HOSu / dimethylformamide

8: TFA

9: TFMSA

With 1-hydroxy-pyrrolidine-2,5-dione; trifluorormethanesulfonic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In N,N-dimethyl-formamide; 1: Condensation / 2: deprotection / 3: Condensation / 4: deprotection / 5: Condensation / 6: deprotection / 7: Condensation / 8: deprotection / 9: deprotection;

DOI:10.1271/bbb.62.1875

upstream raw materials:

1-(tert-butoxycarbonyl)-L-proline

(S)-Leu-OMe

Boc-Arg(Tos)-OH