3-(1H-pyrrol-3-yl)prop-2-enoic acid

Base Information

Chemical Name:3-(1H-pyrrol-3-yl)prop-2-enoic acid
CAS No.:85310-57-2
Molecular Formula:C₇H₇NO₂
Molecular Weight:137.138
Hs Code.:
European Community (EC) Number:867-621-4
Nikkaji Number:J2.362.573C,J2.442.317D

Synonyms:3-(1H-pyrrol-3-yl)prop-2-enoic acid;85310-57-2;3-(1H-Pyrrol-3-yl)acrylic acid;856597-79-0;(E)-3-(1H-pyrrol-3-yl)prop-2-enoic acid;(E)-3-(1H-Pyrrol-3-yl)acrylic acid;(2E)-3-(1H-pyrrol-3-yl)prop-2-enoic acid;3-(3-pyrrolyl)acrylic acid;SCHEMBL2211035;3-(1H-Pyrrol-3-yl)acrylicacid;AKOS006356679;(E)-3-(1H-Pyrrole-3-yl)acrylic acid;(E)-3-(1H-pyrrol-3-yl)-acrylic acid;EN300-97031;EN300-833083;(2E)-3-(1H-Pyrrol-3-yl)-2-propenoic acid #;2-Propenoic acid, 3-(1H-pyrrol-3-yl)-, (E)-;Z1203733427

Suppliers and Price of 3-(1H-pyrrol-3-yl)prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 3-(1H-pyrrol-3-yl)prop-2-enoic acid

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:137.047678466
Heavy Atom Count:10
Complexity:154

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CNC=C1C=CC(=O)O
Isomeric SMILES:C1=CNC=C1/C=C/C(=O)O

Technology Process of 3-(1H-pyrrol-3-yl)prop-2-enoic acid

There total 7 articles about 3-(1H-pyrrol-3-yl)prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 864815-12-3
(E)-3-[1-(toluene-4-sulfonyl)-1H-pyrrol-3-yl]prop-2-enoic acid

: 85310-57-2,856597-79-0
(E)-3-(1H-pyrrol-3-yl)prop-2-enoic acid

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 18h;
DOI:10.1055/s-2006-926426

Reference yield: 75.0%

: 123530-69-8
ethyl 3-(3-pyrrolyl)acrylate

: 85310-57-2,856597-79-0
(E)-3-(1H-pyrrol-3-yl)prop-2-enoic acid

Guidance literature:: With sodium hydroxide; In ethanol; at 90 ℃; for 0.5h;
DOI:10.1248/cpb.37.684

Reference yield:

: 50634-05-4,159551-27-6,159551-33-4,159551-28-7,159551-29-8,159551-30-1,159551-34-5
2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde

: 85310-57-2,856597-79-0
(E)-3-(1H-pyrrol-3-yl)prop-2-enoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: 72 percent / TsOH / toluene / 3 h / Heating

2.1: LDA / tetrahydrofuran; hexane / -78 - 0 °C

2.2: 67 percent / tetrahydrofuran; hexane / 12 h / 0 - 5 °C

3.1: 89 percent / K₂CO₃ / methanol / 18 h / 20 °C

With potassium carbonate; toluene-4-sulfonic acid; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane; toluene; 2.2: Horner-Wadsworth-Emmons reaction;
DOI:10.1055/s-2006-926426