Technology Process of C16-5OXS
There total 5 articles about C16-5OXS which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / 3.5 h / Cooling with ice; Reflux
2.1: magnesium / diethyl ether / Reflux; Inert atmosphere
2.2: 2 h / Reflux; Inert atmosphere
2.3: Inert atmosphere
3.1: 5%-palladium/activated carbon; perchloric acid; hydrogen; acetic acid / 7500.75 Torr
4.1: chlorosulfonic acid / 2 h / 20 °C
With
chlorosulfonic acid; aluminum (III) chloride; perchloric acid; 5%-palladium/activated carbon; hydrogen; magnesium; acetic acid;
In
diethyl ether;
1.1: Friedel-Crafts reaction / 2.2: Grignard reaction / 2.3: Grignard reaction;
DOI:10.1007/s11743-009-1165-z
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / diethyl ether / Reflux; Inert atmosphere
1.2: 2 h / Reflux; Inert atmosphere
1.3: Inert atmosphere
2.1: 5%-palladium/activated carbon; perchloric acid; hydrogen; acetic acid / 7500.75 Torr
3.1: chlorosulfonic acid / 2 h / 20 °C
With
chlorosulfonic acid; perchloric acid; 5%-palladium/activated carbon; hydrogen; magnesium; acetic acid;
In
diethyl ether;
1.2: Grignard reaction / 1.3: Grignard reaction;
DOI:10.1007/s11743-009-1165-z
