Levofloxacin N-oxide

Base Information

Chemical Name:Levofloxacin N-oxide
CAS No.:117678-38-3
Molecular Formula:C₁₈H₂₀FN₃O₅
Molecular Weight:377.372
Hs Code.:
UNII:UE0E2O42UC
DSSTox Substance ID:DTXSID60151865
Nikkaji Number:J386.470G
Wikidata:Q27291038
Mol file:117678-38-3.mol

Synonyms:Levofloxacin N-oxide;117678-38-3;UNII-UE0E2O42UC;UE0E2O42UC;(2S)-7-fluoro-2-methyl-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;(S)-4-(6-Carboxy-9-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-(1,4)oxazino(2,3,4-ij)quinolin-10-yl)-1-methylpiperazine 1-oxide;(S)-4-(6-CARBOXY-9-FLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-[1,4]OXAZINO[2,3,4-IJ]QUINOLIN-10-YL)-1-METHYLPIPERAZINE 1-OXIDE;(S)-4-(6-Carboxy-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-[1,4]oxazino[2,3,4-ij]quinolin-10-yl)-1-methylpiperazine1-oxide;DTXSID60151865;OFLOXACIN N-OXIDE, (S)-;AKOS040756170;CS-O-060110;HY-133787;CS-0132782;F19494;Q27291038;LEVOFLOXACIN HEMIHYDRATE IMPURITY C [EP IMPURITY];LEVOFLOXACIN IMPURITY, LEVOFLOXACIN N-OXIDE- [USP IMPURITY];7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-, (3S)-;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, N-oxide, (S)-;N-Oxide levofloxacin

Suppliers and Price of Levofloxacin N-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
LevofloxacinN-oxide
25mg
$ 180.00

Cayman Chemical
Levofloxacin N-oxide
25mg
$ 281.00

Cayman Chemical
Levofloxacin N-oxide
10mg
$ 163.00

Cayman Chemical
Levofloxacin N-oxide
5mg
$ 94.00

Cayman Chemical
Levofloxacin N-oxide
1mg
$ 25.00

Total 21 raw suppliers

Chemical Property of Levofloxacin N-oxide

Chemical Property:

Melting Point:>146°C (dec.)
PKA:5.19±0.40(Predicted)
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:377.13869891
Heavy Atom Count:27
Complexity:678

Purity/Quality:

99%, ^*data from raw suppliers

LevofloxacinN-oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CC[N+](CC4)(C)[O-])F)C(=O)O
Isomeric SMILES:C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CC[N+](CC4)(C)[O-])F)C(=O)O
Description Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.
Uses Levofloxacin N-oxide is an impurity of Ofloxacin (O245750), which is a fluorinated quinolone antibacterial.

Technology Process of Levofloxacin N-oxide

There total 1 articles about Levofloxacin N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: