1-diethylcarbamoyl-3-formylindole

Base Information

• Chemical Name: 1-diethylcarbamoyl-3-formylindole
• CAS No.: 105949-40-4
• Molecular Formula: C₁₄H₁₆N₂O₂
• Molecular Weight: 244.293
• Mol file: 105949-40-4.mol

Synonyms:

Chemical Property of 1-diethylcarbamoyl-3-formylindole

Chemical Property:

• PSA: 42.31000
• LogP: 2.76370

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-diethylcarbamoyl-3-formylindole

There total 3 articles about 1-diethylcarbamoyl-3-formylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + N,N-diethylcarbamyl chloride (88-10-8) → 1-diethylcarbamoyl-3-formylindole (105949-40-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)84397-X

Reference yield: 77.0%

→ 3-[(4-methoxyphenyl)methyl]-1H-indole (22044-95-7) + 1-diethylcarbamoyl-3-formylindole (105949-40-4)

Guidance literature:

Reference yield:

→ 1-diethylcarbamoyl-3-formylindole (105949-40-4)

Guidance literature:

upstream raw materials:

Indole-3-carboxaldehyde

N,N-diethylcarbamyl chloride

Downstream raw materials:

C₂₀H₂₁⁽²⁾HN₂O

3-(1-phenylbut-3-enyl)indole-1-carboxylic acid diethylamide

3-Benzyl-indole-1-carboxylic acid diethylamide

3-(1-phenylbut-3-en-1-yl)-1H-indole