cis-norcaryophyllenic acid

Base Information

• Chemical Name: cis-norcaryophyllenic acid
• CAS No.: 4614-34-0
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.181
• Mol file: 4614-34-0.mol

Synonyms:

Chemical Property of cis-norcaryophyllenic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-norcaryophyllenic acid

There total 29 articles about cis-norcaryophyllenic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Dehydronorcaryophyllensaeure-dimethylester (4994-59-6) → cis-3,3-Dimethyl-cyclobutan-dicarbonsaeure-(1,2) (496-99-1,4614-34-0,4614-35-1,14385-82-1,15249-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / methanol / Heating

2: H₂ / Pd

With sodium hydroxide; hydrogen; palladium; In methanol;

Reference yield:

cis-1,2-Dichlor-norcaryophyllensaeure (14385-80-9,90322-04-6) → cis-3,3-Dimethyl-cyclobutan-dicarbonsaeure-(1,2) (496-99-1,4614-34-0,4614-35-1,14385-82-1,15249-46-4)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) HCl, (ii) /BRN= 102415/

2: Ni(CO)4 / benzene; dimethylformamide / Heating

3: aq. NaOH / methanol / Heating

4: H₂ / Pd

With sodium hydroxide; hydrogen; tetracarbonyl nickel; palladium; In methanol; N,N-dimethyl-formamide; benzene;

Reference yield:

cis-1,2-Dichlor-norcaryophyllensaeure (14385-80-9,90322-04-6) → DL-trans-Norcaryophyllensaeure (496-99-1,4614-34-0,4614-35-1,14385-82-1,15249-46-4)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) HCl, (ii) /BRN= 102415/

2: H₂ / Raney-Ni / methanol / Heating

3: aq. NaOH / methanol / Heating

With sodium hydroxide; hydrogen; nickel; In methanol;

upstream raw materials:

2,5-dibromo-3,3-dimethyl-adipic acid diethyl ester

cis-3,3-Dimethyl-cyclobutan-dicarbonsaeure-(1,2)

(+)-trans-Norcaryophyllensaeure

acetyl chloride

Downstream raw materials:

DL-trans-Norcaryophyllensaeure

((1R)-3,3-dimethyl-cyclobutane-1r,2t-diyl)-di-acetic acid-dianilide