Technology Process of (S,S(p),S(p))-2-diphenylphosphino-2''-(4-methylphenyl)sulfinyl-1,1''-biferrocene
There total 1 articles about (S,S(p),S(p))-2-diphenylphosphino-2''-(4-methylphenyl)sulfinyl-1,1''-biferrocene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
t-BuLi;
In
tetrahydrofuran; pentane;
under Ar atm. to soln. Fe complex in THF was added dropwise t-BuLi in pentane at -78°C and stirred for 5 min, Ar2PCl was added and warmedto r.t. and stirred for 16 h; react. mixt. was quenched with aq. NaHCO3, org. phase was separated, washed with water and dried over MgSO4, solvent was removed in vacuo, residue was chromd. on silica (PE-acetone-Et3N 100:20:1 -> 10:10:1); elem. anal.;
DOI:10.1039/b816544k
- Guidance literature:
-
With
t-BuLi;
In
tetrahydrofuran; pentane;
under Ar atm. to soln. Fe complex in THF t-BuLi in pentane was added at -78°C, stirred for 5 min, R2PCl was added, allowed to warm to r.t. and stirred for 16 h; react. mixt. was quenched with aq. NaHCO3, org. phase was separated, washed with water and dried over MgSO4, solvent was removed in vacuo, residue was chromd. on alumina (PE-Et2O-Et3N 100:2:1 -> 60:3:1 -> 20:3:1); elem. anal.;
DOI:10.1039/b816544k
