N-Pelargonoyldopamine

Base Information

• Chemical Name: N-Pelargonoyldopamine
• CAS No.: 105955-08-6
• Molecular Formula: C17H27NO3
• Molecular Weight: 293.406
• UNII: HC7N5Y8H0F
• Nikkaji Number: J467.917B
• Wikidata: Q27279859
• Mol file: 105955-08-6.mol

Synonyms:N-Pelargonoyldopamine;UNII-HC7N5Y8H0F;HC7N5Y8H0F;105955-08-6;Nonanamide, N-(2-(3,4-dihydroxyphenyl)ethyl)-;N-[2-(3,4-Dihydroxyphenyl)ethyl]nonanamide;nonanoyl dopamine;AKOS033805001;Q27279859;Z221503636

Chemical Property of N-Pelargonoyldopamine

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 10
• Exact Mass: 293.19909372
• Heavy Atom Count: 21
• Complexity: 283

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCC(=O)NCCC1=CC(=C(C=C1)O)O

Technology Process of N-Pelargonoyldopamine

There total 4 articles about N-Pelargonoyldopamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

dopamine (51-61-6) + nonanoic acid (112-05-0) → N-(3,4-dihydroxyphenethyl)nonanamide (105955-08-6)

Guidance literature:

dopamine; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

nonanoic acid; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/anie.201410672

Reference yield:

nonanoic acid (112-05-0) → N-(3,4-dihydroxyphenethyl)nonanamide (105955-08-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 0.25 h

2: Et₃N / tetrahydrofuran / Ambient temperature

With triethylamine; In tetrahydrofuran;

DOI:10.1248/cpb.40.396

Reference yield:

dopamine hydrochloride (62-31-7) + C14H26O4 → N-(3,4-dihydroxyphenethyl)nonanamide (105955-08-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; Yield given; Ambient temperature;

DOI:10.1248/cpb.40.396

upstream raw materials:

dopamine hydrochloride

nonanoic acid

dopamine