Technology Process of tert-butyl 2-phenyl sulfone
There total 3 articles about tert-butyl 2-phenyl sulfone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium perborate tetrahydrate / acetic acid / 3 h / 50 °C
2: 1.) BuLi / 1) THF, hexane, -70 deg C, 30 min; 2) THF, hexane, -70 deg C --> room temperature, 2 h
With
sodium perborate; n-butyllithium;
In
acetic acid;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / Amberlyst H-15 / diethyl ether / 72 h / -78 - 20 °C
2: sodium perborate tetrahydrate / acetic acid / 3 h / 50 °C
3: 1.) BuLi / 1) THF, hexane, -70 deg C, 30 min; 2) THF, hexane, -70 deg C --> room temperature, 2 h
With
sodium perborate; n-butyllithium; Amberlyst H-15;
In
diethyl ether; acetic acid;
- Guidance literature:
-
With
n-butyllithium;
Yield given. Multistep reaction;
1) THF, hexane, -70 deg C, 30 min; 2) THF, hexane, -70 deg C --> room temperature, 2 h;
