sporaricin B base

Base Information

Chemical Name:sporaricin B base
CAS No.:83648-64-0
Molecular Formula:C₁₅H₃₂N₄O₄
Molecular Weight:332.443
Hs Code.:

Synonyms:

Suppliers and Price of sporaricin B base

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of sporaricin B base

Chemical Property:

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Technology Process of sporaricin B base

There total 1 articles about sporaricin B base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68743-78-2,71657-28-8,75829-53-7,81738-62-7,81768-56-1,81800-11-5,83648-64-0
3-Amino-2-[3-amino-6-((S)-1-amino-ethyl)-tetrahydro-pyran-2-yloxy]-5-methoxy-6-methylamino-cyclohexanol

Guidance literature:: durch Saccharopolyspora hirsuta subsp. kobensis prod. (isoliert als Monohydrat);
DOI:10.7164/antibiotics.32.173

Reference yield: 90.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 68743-78-2,71657-28-8,75829-53-7,81738-62-7,81768-56-1,81800-11-5,83648-64-0
sporaricin B base

: 74556-46-0,78340-65-5
{(1S,2R,3R,4R,6S)-4-Benzyloxycarbonylamino-3-[(2R,3R,6S)-3-benzyloxycarbonylamino-6-((R)-1-benzyloxycarbonylamino-ethyl)-tetrahydro-pyran-2-yloxy]-2-hydroxy-6-methoxy-cyclohexyl}-methyl-carbamic acid benzyl ester

Guidance literature:: DOI:10.1016/0008-6215(83)88118-X

Reference yield:

: 68743-78-2,71657-28-8,75829-53-7,81738-62-7,81768-56-1,81800-11-5,83648-64-0
sporaricin B base

: 86651-60-7
[({(1R,2R,3R,4R,6S)-4-Amino-3-[(2R,3R,6S)-3-amino-6-((R)-1-amino-ethyl)-tetrahydro-pyran-2-yloxy]-2-fluoro-6-methoxy-cyclohexyl}-methyl-carbamoyl)-methyl]-carbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 90 percent

2: 31 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 1.) 15 min, -15 deg C; 2.) 30 min, r.t.

3: 79 percent / 0.2 M hydrochloric acid, hydrogen / 10 percent palladium-on-charcoal / methanol / 4 h / 760 Torr

4: 405 mg / methanol / 1 h / Heating

5: triethylamine / various solvent(s) / 37 °C / Heating

6: 372 mg / 0.2 M hydrochloric acid / H₂O

With hydrogenchloride; diethylamino-sulfur trifluoride; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; water;
DOI:10.1016/0008-6215(83)88118-X